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Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles

Aim: The purpose of this study was to compare neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and mean platelet volume (MPV) values of patients with measles within the healthy control group and then determine the utility of these parameters for determination of inflammatory situa...

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Autores principales: Solmaz, Abdullah, Demir, Abit, Gümüş, Hüseyin, Aksoy, Mustafa, Solmaz, Filiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008753/
https://www.ncbi.nlm.nih.gov/pubmed/32064188
http://dx.doi.org/10.7759/cureus.6607
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author Solmaz, Abdullah
Demir, Abit
Gümüş, Hüseyin
Aksoy, Mustafa
Solmaz, Filiz
author_facet Solmaz, Abdullah
Demir, Abit
Gümüş, Hüseyin
Aksoy, Mustafa
Solmaz, Filiz
author_sort Solmaz, Abdullah
collection PubMed
description Aim: The purpose of this study was to compare neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and mean platelet volume (MPV) values of patients with measles within the healthy control group and then determine the utility of these parameters for determination of inflammatory situation in patients with measles. Materials and method: A total of 51 pediatric patients who had visited Harran University Medical Faculty Pediatrics Clinic between June 2018 and May 2019 and who had been diagnosed with measles after anamnesis, clinical, and serological evaluations were included our study; 49 healthy children who visited our clinic for various reasons and had taken hemogram tests were also added to our study as the control group. Results: NLR and PLR values were observed higher than the control group for patients diagnosed with measles; however, the difference between the two groups was not statistically significant (p values 0.515 and 0.796, respectively). When MPV values of patients diagnosed with measles and control groups were compared, it was determined that MPV value was statistically lower in patients diagnosed with measles (p: 0.001). Conclusion: Based on the parameters obtained through our study, it can be said that NLR and PLR are not suitable parameters for proving inflammation in patients with measles but MPV can be used as a convenient parameter for that purpose. However, prospective studies conducted with more patients are needed in this respect.
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spelling pubmed-70087532020-02-15 Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles Solmaz, Abdullah Demir, Abit Gümüş, Hüseyin Aksoy, Mustafa Solmaz, Filiz Cureus Dermatology Aim: The purpose of this study was to compare neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and mean platelet volume (MPV) values of patients with measles within the healthy control group and then determine the utility of these parameters for determination of inflammatory situation in patients with measles. Materials and method: A total of 51 pediatric patients who had visited Harran University Medical Faculty Pediatrics Clinic between June 2018 and May 2019 and who had been diagnosed with measles after anamnesis, clinical, and serological evaluations were included our study; 49 healthy children who visited our clinic for various reasons and had taken hemogram tests were also added to our study as the control group. Results: NLR and PLR values were observed higher than the control group for patients diagnosed with measles; however, the difference between the two groups was not statistically significant (p values 0.515 and 0.796, respectively). When MPV values of patients diagnosed with measles and control groups were compared, it was determined that MPV value was statistically lower in patients diagnosed with measles (p: 0.001). Conclusion: Based on the parameters obtained through our study, it can be said that NLR and PLR are not suitable parameters for proving inflammation in patients with measles but MPV can be used as a convenient parameter for that purpose. However, prospective studies conducted with more patients are needed in this respect. Cureus 2020-01-09 /pmc/articles/PMC7008753/ /pubmed/32064188 http://dx.doi.org/10.7759/cureus.6607 Text en Copyright © 2020, Solmaz et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Solmaz, Abdullah
Demir, Abit
Gümüş, Hüseyin
Aksoy, Mustafa
Solmaz, Filiz
Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles
title Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles
title_full Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles
title_fullStr Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles
title_full_unstemmed Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles
title_short Neutrophil/Lymphocyte Ratios, Platelet/Lymphocyte Ratios, and Mean Platelet Volume Values in Patients with Measles
title_sort neutrophil/lymphocyte ratios, platelet/lymphocyte ratios, and mean platelet volume values in patients with measles
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008753/
https://www.ncbi.nlm.nih.gov/pubmed/32064188
http://dx.doi.org/10.7759/cureus.6607
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