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Establishment of cumulative assessment groups of pesticides for their effects on the thyroid

Cumulative assessment groups of pesticides have been established for two specific effects on the thyroid: firstly hypothyroidism, and secondly parafollicular cell (C‐cell) hypertrophy, hyperplasia and neoplasia. Sources of uncertainties resulting from the methodological approach and from the limitat...

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Autores principales: Crivellente, Federica, Hart, Andy, Hernandez‐Jerez, Antonio F., Hougaard Bennekou, Susanne, Pedersen, Ragnor, Terron, Andrea, Wolterink, Gerrit, Mohimont, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009157/
https://www.ncbi.nlm.nih.gov/pubmed/32626429
http://dx.doi.org/10.2903/j.efsa.2019.5801
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author Crivellente, Federica
Hart, Andy
Hernandez‐Jerez, Antonio F.
Hougaard Bennekou, Susanne
Pedersen, Ragnor
Terron, Andrea
Wolterink, Gerrit
Mohimont, Luc
author_facet Crivellente, Federica
Hart, Andy
Hernandez‐Jerez, Antonio F.
Hougaard Bennekou, Susanne
Pedersen, Ragnor
Terron, Andrea
Wolterink, Gerrit
Mohimont, Luc
collection PubMed
description Cumulative assessment groups of pesticides have been established for two specific effects on the thyroid: firstly hypothyroidism, and secondly parafollicular cell (C‐cell) hypertrophy, hyperplasia and neoplasia. Sources of uncertainties resulting from the methodological approach and from the limitations in available data and scientific knowledge have been identified and considered. This report supports the publication of a scientific report on cumulative risk assessment to pesticides affecting the thyroid, in which all uncertainties identified for either the exposure assessment or the establishment of the cumulative assessment groups are incorporated into a consolidated risk characterisation.
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spelling pubmed-70091572020-07-02 Establishment of cumulative assessment groups of pesticides for their effects on the thyroid Crivellente, Federica Hart, Andy Hernandez‐Jerez, Antonio F. Hougaard Bennekou, Susanne Pedersen, Ragnor Terron, Andrea Wolterink, Gerrit Mohimont, Luc EFSA J Scientific Report Cumulative assessment groups of pesticides have been established for two specific effects on the thyroid: firstly hypothyroidism, and secondly parafollicular cell (C‐cell) hypertrophy, hyperplasia and neoplasia. Sources of uncertainties resulting from the methodological approach and from the limitations in available data and scientific knowledge have been identified and considered. This report supports the publication of a scientific report on cumulative risk assessment to pesticides affecting the thyroid, in which all uncertainties identified for either the exposure assessment or the establishment of the cumulative assessment groups are incorporated into a consolidated risk characterisation. John Wiley and Sons Inc. 2019-09-17 /pmc/articles/PMC7009157/ /pubmed/32626429 http://dx.doi.org/10.2903/j.efsa.2019.5801 Text en © 2019 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Report
Crivellente, Federica
Hart, Andy
Hernandez‐Jerez, Antonio F.
Hougaard Bennekou, Susanne
Pedersen, Ragnor
Terron, Andrea
Wolterink, Gerrit
Mohimont, Luc
Establishment of cumulative assessment groups of pesticides for their effects on the thyroid
title Establishment of cumulative assessment groups of pesticides for their effects on the thyroid
title_full Establishment of cumulative assessment groups of pesticides for their effects on the thyroid
title_fullStr Establishment of cumulative assessment groups of pesticides for their effects on the thyroid
title_full_unstemmed Establishment of cumulative assessment groups of pesticides for their effects on the thyroid
title_short Establishment of cumulative assessment groups of pesticides for their effects on the thyroid
title_sort establishment of cumulative assessment groups of pesticides for their effects on the thyroid
topic Scientific Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009157/
https://www.ncbi.nlm.nih.gov/pubmed/32626429
http://dx.doi.org/10.2903/j.efsa.2019.5801
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