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Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005
According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance clethodim. To assess the occurrence of clethodim residues in plants, processed commodities, rotational crops and live...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009186/ https://www.ncbi.nlm.nih.gov/pubmed/32626327 http://dx.doi.org/10.2903/j.efsa.2019.5706 |
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author | Anastassiadou, Maria Brancato, Alba Carrasco Cabrera, Luis Ferreira, Lucien Greco, Luna Jarrah, Samira Kazocina, Aija Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Pedersen, Ragnor Raczyk, Marianna Reich, Hermine Ruocco, Silvia Sacchi, Angela Santos, Miguel Stanek, Alois Tarazona, Jose Theobald, Anne Verani, Alessia |
author_facet | Anastassiadou, Maria Brancato, Alba Carrasco Cabrera, Luis Ferreira, Lucien Greco, Luna Jarrah, Samira Kazocina, Aija Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Pedersen, Ragnor Raczyk, Marianna Reich, Hermine Ruocco, Silvia Sacchi, Angela Santos, Miguel Stanek, Alois Tarazona, Jose Theobald, Anne Verani, Alessia |
collection | PubMed |
description | According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance clethodim. To assess the occurrence of clethodim residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission and European authorisations reported by Member States (including the supporting residues data). Based on the assessment of the available data, MRL could not be proposed because an overall consumer risk assessment could not be finalised. Risk managers should be made aware that the genotoxic potential of the clethodim metabolite 3‐chloroallyl alcohol, the aglycon of 3‐chlorolallyl alcohol glucoside (M14A/M15A) could not be concluded and no toxicological reference values could be derived for this metabolite. Until a conclusion on the toxicological properties of the metabolite is reached, a decision on the residue definition for risk assessment cannot be made which is a prerequisite to perform a reliable dietary risk assessment. |
format | Online Article Text |
id | pubmed-7009186 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70091862020-07-02 Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005 Anastassiadou, Maria Brancato, Alba Carrasco Cabrera, Luis Ferreira, Lucien Greco, Luna Jarrah, Samira Kazocina, Aija Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Pedersen, Ragnor Raczyk, Marianna Reich, Hermine Ruocco, Silvia Sacchi, Angela Santos, Miguel Stanek, Alois Tarazona, Jose Theobald, Anne Verani, Alessia EFSA J Reasoned Opinion According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance clethodim. To assess the occurrence of clethodim residues in plants, processed commodities, rotational crops and livestock, EFSA considered the conclusions derived in the framework of Directive 91/414/EEC, the MRLs established by the Codex Alimentarius Commission and European authorisations reported by Member States (including the supporting residues data). Based on the assessment of the available data, MRL could not be proposed because an overall consumer risk assessment could not be finalised. Risk managers should be made aware that the genotoxic potential of the clethodim metabolite 3‐chloroallyl alcohol, the aglycon of 3‐chlorolallyl alcohol glucoside (M14A/M15A) could not be concluded and no toxicological reference values could be derived for this metabolite. Until a conclusion on the toxicological properties of the metabolite is reached, a decision on the residue definition for risk assessment cannot be made which is a prerequisite to perform a reliable dietary risk assessment. John Wiley and Sons Inc. 2019-05-22 /pmc/articles/PMC7009186/ /pubmed/32626327 http://dx.doi.org/10.2903/j.efsa.2019.5706 Text en © 2019 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Reasoned Opinion Anastassiadou, Maria Brancato, Alba Carrasco Cabrera, Luis Ferreira, Lucien Greco, Luna Jarrah, Samira Kazocina, Aija Leuschner, Renata Magrans, Jose Oriol Miron, Ileana Pedersen, Ragnor Raczyk, Marianna Reich, Hermine Ruocco, Silvia Sacchi, Angela Santos, Miguel Stanek, Alois Tarazona, Jose Theobald, Anne Verani, Alessia Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005 |
title | Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005 |
title_full | Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005 |
title_fullStr | Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005 |
title_full_unstemmed | Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005 |
title_short | Review of the existing maximum residue levels for clethodim according to Article 12 of Regulation (EC) No 396/2005 |
title_sort | review of the existing maximum residue levels for clethodim according to article 12 of regulation (ec) no 396/2005 |
topic | Reasoned Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009186/ https://www.ncbi.nlm.nih.gov/pubmed/32626327 http://dx.doi.org/10.2903/j.efsa.2019.5706 |
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