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Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on safety and efficacy of sodium molybdate dihydrate for sheep, based on a dossier submitted for the re‐evaluation of the additiv...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Kouba, Maryline, Kos Durjava, Mojca, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Flachowsky, Gerhard, Gropp, Jürgen, Cubadda, Francesco, López‐Gálvez, Gloria, Mantovani, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009221/
https://www.ncbi.nlm.nih.gov/pubmed/32626229
http://dx.doi.org/10.2903/j.efsa.2019.5606
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Flachowsky, Gerhard
Gropp, Jürgen
Cubadda, Francesco
López‐Gálvez, Gloria
Mantovani, Alberto
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Flachowsky, Gerhard
Gropp, Jürgen
Cubadda, Francesco
López‐Gálvez, Gloria
Mantovani, Alberto
collection PubMed
description Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on safety and efficacy of sodium molybdate dihydrate for sheep, based on a dossier submitted for the re‐evaluation of the additive. The additive is currently authorised in the EU for all animal species as ‘Nutritional additive’ – ‘Compounds of trace elements’. Taking the optimal Cu:Mo ratio of 3–10, and the highest total copper level authorised in complete feeds for sheep (15 mg/kg), the FEEDAP Panel concluded that 2.5 mg total Mo/kg complete feed is safe for sheep. Considering (i) a safe intake of 0.6 mg Mo/day, (ii) the estimate average intake figure from food in Europe (generally less than 100 μg/day), (iii) the contribution of foods of animal origin to the total molybdenum intake (estimated to be up to 22 %), and (iv) that molybdenum would not accumulate in edible tissues/products of sheep fed molybdenum supplemented diets up to the upper safe level, the FEEDAP Panel concluded that the use of sodium molybdate as a additive in sheep at 2.5 mg total Mo/kg complete feed is safe for consumers. The additive under assessment feed poses no risk by inhalation to users; it is a skin and eye irritant, but it is not considered as a skin sensitiser. Sodium molybdate used up to 2.5 mg Mo/kg complete sheep feed poses no concerns for the safety for the environment. The FEEDAP Panel recognises that molybdenum does not need to be added to diets to cover the nutritional needs of molybdenum of sheep. Molybdenum supplementation in sheep feed is considered effective in order to guarantee an adequate balance with copper, when the Cu:Mo ratio in the diet is in the range 3–10.
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spelling pubmed-70092212020-07-02 Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V. Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Flachowsky, Gerhard Gropp, Jürgen Cubadda, Francesco López‐Gálvez, Gloria Mantovani, Alberto EFSA J Scientific Opinion Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on safety and efficacy of sodium molybdate dihydrate for sheep, based on a dossier submitted for the re‐evaluation of the additive. The additive is currently authorised in the EU for all animal species as ‘Nutritional additive’ – ‘Compounds of trace elements’. Taking the optimal Cu:Mo ratio of 3–10, and the highest total copper level authorised in complete feeds for sheep (15 mg/kg), the FEEDAP Panel concluded that 2.5 mg total Mo/kg complete feed is safe for sheep. Considering (i) a safe intake of 0.6 mg Mo/day, (ii) the estimate average intake figure from food in Europe (generally less than 100 μg/day), (iii) the contribution of foods of animal origin to the total molybdenum intake (estimated to be up to 22 %), and (iv) that molybdenum would not accumulate in edible tissues/products of sheep fed molybdenum supplemented diets up to the upper safe level, the FEEDAP Panel concluded that the use of sodium molybdate as a additive in sheep at 2.5 mg total Mo/kg complete feed is safe for consumers. The additive under assessment feed poses no risk by inhalation to users; it is a skin and eye irritant, but it is not considered as a skin sensitiser. Sodium molybdate used up to 2.5 mg Mo/kg complete sheep feed poses no concerns for the safety for the environment. The FEEDAP Panel recognises that molybdenum does not need to be added to diets to cover the nutritional needs of molybdenum of sheep. Molybdenum supplementation in sheep feed is considered effective in order to guarantee an adequate balance with copper, when the Cu:Mo ratio in the diet is in the range 3–10. John Wiley and Sons Inc. 2019-02-27 /pmc/articles/PMC7009221/ /pubmed/32626229 http://dx.doi.org/10.2903/j.efsa.2019.5606 Text en © 2019 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Flachowsky, Gerhard
Gropp, Jürgen
Cubadda, Francesco
López‐Gálvez, Gloria
Mantovani, Alberto
Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.
title Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.
title_full Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.
title_fullStr Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.
title_full_unstemmed Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.
title_short Safety and efficacy of a molybdenum compound (E7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by Trouw Nutrition International B.V.
title_sort safety and efficacy of a molybdenum compound (e7) sodium molybdate dihydrate as feed additive for sheep based on a dossier submitted by trouw nutrition international b.v.
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009221/
https://www.ncbi.nlm.nih.gov/pubmed/32626229
http://dx.doi.org/10.2903/j.efsa.2019.5606
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