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Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009239/ https://www.ncbi.nlm.nih.gov/pubmed/32626273 http://dx.doi.org/10.2903/j.efsa.2019.5654 |
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author | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Brantom, Paul Chesson, Andrew Westendorf, Johannes Gregoretti, Lucilla Manini, Paola Dusemund, Birgit |
author_facet | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Brantom, Paul Chesson, Andrew Westendorf, Johannes Gregoretti, Lucilla Manini, Paola Dusemund, Birgit |
collection | PubMed |
description | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters). They are all currently authorised as flavours in food. The FEEDAP Panel was unable to perform the assessment of non‐2(cis)‐en‐1‐ol [02.112] in the absence of data on its purity. The FEEDAP Panel concludes that hex‐2‐en‐1‐ol [02.020], pent‐2‐en‐1‐ol [02.050], 2‐dodecenal [05.037], nona‐2,4‐dienal [05.071], trans‐2‐nonenal [05.072], hex‐2(trans)‐enal [05.073], 2,4‐decadienal [05.081], hepta‐2,4‐dienal [05.084], deca‐2(trans),4(trans)‐dienal [05.140], dodec‐2(trans)‐enal [05.144], hept‐2(trans)‐enal [05.150], non‐2‐enal [05.171], undec‐2(trans)‐enal [05.184], trans‐2‐octenal [05.190], trans‐2‐decenal [05.191], tr‐2, tr‐4‐nonadienal [05.194], tr‐2, tr‐4‐undecadienal [05.196], hex‐2(trans)‐enyl acetate [09.394] and hex‐2‐enyl butyrate [09.396] are safe at the proposed maximum use level of 5 mg/kg feed for all animal species; nona‐2,6‐dien‐1‐ol [02.049], trans‐2, cis‐6‐nonadien‐1‐ol [02.231], nona‐2(trans),6(cis)‐dienal [05.058], nona‐2(trans),6(trans)‐dienal [05.172], allyl heptanoate [09.097] and allyl hexanoate [09.244] are safe at the proposed normal use levels of 1 mg/kg complete feed for all animal species. No safety concern would arise for the consumer from the use of these compounds up to the highest safe levels in feed. In the absence of studies to assess the safety for the user, the FEEDAP Panel cannot conclude on the safety for the users when handling the additives. No environmental risk is foreseen for these compounds at the concentrations considered safe for the target species. Since the 25 compounds are used in food as flavourings and their function is essentially the same as that in food, no further demonstration of efficacy is necessary. |
format | Online Article Text |
id | pubmed-7009239 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70092392020-07-02 Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Brantom, Paul Chesson, Andrew Westendorf, Johannes Gregoretti, Lucilla Manini, Paola Dusemund, Birgit EFSA J Scientific Opinion Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters). They are all currently authorised as flavours in food. The FEEDAP Panel was unable to perform the assessment of non‐2(cis)‐en‐1‐ol [02.112] in the absence of data on its purity. The FEEDAP Panel concludes that hex‐2‐en‐1‐ol [02.020], pent‐2‐en‐1‐ol [02.050], 2‐dodecenal [05.037], nona‐2,4‐dienal [05.071], trans‐2‐nonenal [05.072], hex‐2(trans)‐enal [05.073], 2,4‐decadienal [05.081], hepta‐2,4‐dienal [05.084], deca‐2(trans),4(trans)‐dienal [05.140], dodec‐2(trans)‐enal [05.144], hept‐2(trans)‐enal [05.150], non‐2‐enal [05.171], undec‐2(trans)‐enal [05.184], trans‐2‐octenal [05.190], trans‐2‐decenal [05.191], tr‐2, tr‐4‐nonadienal [05.194], tr‐2, tr‐4‐undecadienal [05.196], hex‐2(trans)‐enyl acetate [09.394] and hex‐2‐enyl butyrate [09.396] are safe at the proposed maximum use level of 5 mg/kg feed for all animal species; nona‐2,6‐dien‐1‐ol [02.049], trans‐2, cis‐6‐nonadien‐1‐ol [02.231], nona‐2(trans),6(cis)‐dienal [05.058], nona‐2(trans),6(trans)‐dienal [05.172], allyl heptanoate [09.097] and allyl hexanoate [09.244] are safe at the proposed normal use levels of 1 mg/kg complete feed for all animal species. No safety concern would arise for the consumer from the use of these compounds up to the highest safe levels in feed. In the absence of studies to assess the safety for the user, the FEEDAP Panel cannot conclude on the safety for the users when handling the additives. No environmental risk is foreseen for these compounds at the concentrations considered safe for the target species. Since the 25 compounds are used in food as flavourings and their function is essentially the same as that in food, no further demonstration of efficacy is necessary. John Wiley and Sons Inc. 2019-03-19 /pmc/articles/PMC7009239/ /pubmed/32626273 http://dx.doi.org/10.2903/j.efsa.2019.5654 Text en © 2019 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Brantom, Paul Chesson, Andrew Westendorf, Johannes Gregoretti, Lucilla Manini, Paola Dusemund, Birgit Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories |
title | Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories |
title_full | Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories |
title_fullStr | Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories |
title_full_unstemmed | Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories |
title_short | Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories |
title_sort | safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009239/ https://www.ncbi.nlm.nih.gov/pubmed/32626273 http://dx.doi.org/10.2903/j.efsa.2019.5654 |
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