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Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Kouba, Maryline, Kos Durjava, Mojca, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Brantom, Paul, Chesson, Andrew, Westendorf, Johannes, Gregoretti, Lucilla, Manini, Paola, Dusemund, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009239/
https://www.ncbi.nlm.nih.gov/pubmed/32626273
http://dx.doi.org/10.2903/j.efsa.2019.5654
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Brantom, Paul
Chesson, Andrew
Westendorf, Johannes
Gregoretti, Lucilla
Manini, Paola
Dusemund, Birgit
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Brantom, Paul
Chesson, Andrew
Westendorf, Johannes
Gregoretti, Lucilla
Manini, Paola
Dusemund, Birgit
collection PubMed
description Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters). They are all currently authorised as flavours in food. The FEEDAP Panel was unable to perform the assessment of non‐2(cis)‐en‐1‐ol [02.112] in the absence of data on its purity. The FEEDAP Panel concludes that hex‐2‐en‐1‐ol [02.020], pent‐2‐en‐1‐ol [02.050], 2‐dodecenal [05.037], nona‐2,4‐dienal [05.071], trans‐2‐nonenal [05.072], hex‐2(trans)‐enal [05.073], 2,4‐decadienal [05.081], hepta‐2,4‐dienal [05.084], deca‐2(trans),4(trans)‐dienal [05.140], dodec‐2(trans)‐enal [05.144], hept‐2(trans)‐enal [05.150], non‐2‐enal [05.171], undec‐2(trans)‐enal [05.184], trans‐2‐octenal [05.190], trans‐2‐decenal [05.191], tr‐2, tr‐4‐nonadienal [05.194], tr‐2, tr‐4‐undecadienal [05.196], hex‐2(trans)‐enyl acetate [09.394] and hex‐2‐enyl butyrate [09.396] are safe at the proposed maximum use level of 5 mg/kg feed for all animal species; nona‐2,6‐dien‐1‐ol [02.049], trans‐2, cis‐6‐nonadien‐1‐ol [02.231], nona‐2(trans),6(cis)‐dienal [05.058], nona‐2(trans),6(trans)‐dienal [05.172], allyl heptanoate [09.097] and allyl hexanoate [09.244] are safe at the proposed normal use levels of 1 mg/kg complete feed for all animal species. No safety concern would arise for the consumer from the use of these compounds up to the highest safe levels in feed. In the absence of studies to assess the safety for the user, the FEEDAP Panel cannot conclude on the safety for the users when handling the additives. No environmental risk is foreseen for these compounds at the concentrations considered safe for the target species. Since the 25 compounds are used in food as flavourings and their function is essentially the same as that in food, no further demonstration of efficacy is necessary.
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spelling pubmed-70092392020-07-02 Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Brantom, Paul Chesson, Andrew Westendorf, Johannes Gregoretti, Lucilla Manini, Paola Dusemund, Birgit EFSA J Scientific Opinion Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters). They are all currently authorised as flavours in food. The FEEDAP Panel was unable to perform the assessment of non‐2(cis)‐en‐1‐ol [02.112] in the absence of data on its purity. The FEEDAP Panel concludes that hex‐2‐en‐1‐ol [02.020], pent‐2‐en‐1‐ol [02.050], 2‐dodecenal [05.037], nona‐2,4‐dienal [05.071], trans‐2‐nonenal [05.072], hex‐2(trans)‐enal [05.073], 2,4‐decadienal [05.081], hepta‐2,4‐dienal [05.084], deca‐2(trans),4(trans)‐dienal [05.140], dodec‐2(trans)‐enal [05.144], hept‐2(trans)‐enal [05.150], non‐2‐enal [05.171], undec‐2(trans)‐enal [05.184], trans‐2‐octenal [05.190], trans‐2‐decenal [05.191], tr‐2, tr‐4‐nonadienal [05.194], tr‐2, tr‐4‐undecadienal [05.196], hex‐2(trans)‐enyl acetate [09.394] and hex‐2‐enyl butyrate [09.396] are safe at the proposed maximum use level of 5 mg/kg feed for all animal species; nona‐2,6‐dien‐1‐ol [02.049], trans‐2, cis‐6‐nonadien‐1‐ol [02.231], nona‐2(trans),6(cis)‐dienal [05.058], nona‐2(trans),6(trans)‐dienal [05.172], allyl heptanoate [09.097] and allyl hexanoate [09.244] are safe at the proposed normal use levels of 1 mg/kg complete feed for all animal species. No safety concern would arise for the consumer from the use of these compounds up to the highest safe levels in feed. In the absence of studies to assess the safety for the user, the FEEDAP Panel cannot conclude on the safety for the users when handling the additives. No environmental risk is foreseen for these compounds at the concentrations considered safe for the target species. Since the 25 compounds are used in food as flavourings and their function is essentially the same as that in food, no further demonstration of efficacy is necessary. John Wiley and Sons Inc. 2019-03-19 /pmc/articles/PMC7009239/ /pubmed/32626273 http://dx.doi.org/10.2903/j.efsa.2019.5654 Text en © 2019 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Brantom, Paul
Chesson, Andrew
Westendorf, Johannes
Gregoretti, Lucilla
Manini, Paola
Dusemund, Birgit
Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
title Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
title_full Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
title_fullStr Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
title_full_unstemmed Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
title_short Safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
title_sort safety and efficacy of 26 compounds belonging to chemical group 3 (α,β‐unsaturated straight‐chain and branched‐chain aliphatic primary alcohols, aldehydes, acids and esters) when used as flavourings for all animal species and categories
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009239/
https://www.ncbi.nlm.nih.gov/pubmed/32626273
http://dx.doi.org/10.2903/j.efsa.2019.5654
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