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Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay

The additive (trade name Biomin(®)DC‐P) is a blend of five individual compounds (carvacrol, thymol, d‐carvone, methyl salicylate and l‐menthol) encapsulated with a hydrogenated vegetable oil. The additive is intended for use in feed for various poultry species at a minimum concentration of 65 mg/kg...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, de Lourdes Bastos, Maria, Christensen, Henrik, Dusemund, Birgit, Kouba, Maryline, Kos Durjava, Mojca, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Chesson, Andrew, Gropp, Jürgen, Martelli, Giovanna, Renshaw, Derek, López‐Gálvez, Gloria, Mantovani, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009287/
https://www.ncbi.nlm.nih.gov/pubmed/32626346
http://dx.doi.org/10.2903/j.efsa.2019.5724
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author Bampidis, Vasileios
Azimonti, Giovanna
de Lourdes Bastos, Maria
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Chesson, Andrew
Gropp, Jürgen
Martelli, Giovanna
Renshaw, Derek
López‐Gálvez, Gloria
Mantovani, Alberto
author_facet Bampidis, Vasileios
Azimonti, Giovanna
de Lourdes Bastos, Maria
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Chesson, Andrew
Gropp, Jürgen
Martelli, Giovanna
Renshaw, Derek
López‐Gálvez, Gloria
Mantovani, Alberto
collection PubMed
description The additive (trade name Biomin(®)DC‐P) is a blend of five individual compounds (carvacrol, thymol, d‐carvone, methyl salicylate and l‐menthol) encapsulated with a hydrogenated vegetable oil. The additive is intended for use in feed for various poultry species at a minimum concentration of 65 mg/kg complete feed and a recommended maximum level of 105 mg/kg complete feed. The results of a tolerance study show that Biomin(®) DC‐P is safe for chickens for fattening at the maximum recommended application rate of 105 mg/kg complete feed; this conclusion is extended to include chickens reared for laying and extrapolated to minor poultry species The active components of a previously evaluated additive (Biomin(®)DC‐C) were shown to be not genotoxic; owing to the similarity on composition, this conclusion can be also applied to Biomin(®)DC‐P. Notwithstanding the uncertainties identified in the residue study, after applying a worst‐case scenario to calculate potential exposure of consumers to menthol and carvone, and since that the components of the additive are considered safe for their use as food and feed flavourings, the FEEDAP Panel concludes that the use of the additive in animal nutrition is considered safe for consumers. The FEEDAP Panel considered that exposure of users by inhalation is unlikely, but cannot conclude on the effects of Biomin(®)DC‐P on skin and eyes. The use of Biomin(®)DC‐P is not expected to pose a risk for the environment. Biomin(®)DC‐P has a potential to increase the growth performance of chickens for fattening when incorporated into feed at a minimum application rate of 65 mg/kg complete feed; the conclusion can be extended to chickens reared for laying and extrapolated to minor poultry species reared up to the point of lay.
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spelling pubmed-70092872020-07-02 Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay Bampidis, Vasileios Azimonti, Giovanna de Lourdes Bastos, Maria Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Chesson, Andrew Gropp, Jürgen Martelli, Giovanna Renshaw, Derek López‐Gálvez, Gloria Mantovani, Alberto EFSA J Scientific Opinion The additive (trade name Biomin(®)DC‐P) is a blend of five individual compounds (carvacrol, thymol, d‐carvone, methyl salicylate and l‐menthol) encapsulated with a hydrogenated vegetable oil. The additive is intended for use in feed for various poultry species at a minimum concentration of 65 mg/kg complete feed and a recommended maximum level of 105 mg/kg complete feed. The results of a tolerance study show that Biomin(®) DC‐P is safe for chickens for fattening at the maximum recommended application rate of 105 mg/kg complete feed; this conclusion is extended to include chickens reared for laying and extrapolated to minor poultry species The active components of a previously evaluated additive (Biomin(®)DC‐C) were shown to be not genotoxic; owing to the similarity on composition, this conclusion can be also applied to Biomin(®)DC‐P. Notwithstanding the uncertainties identified in the residue study, after applying a worst‐case scenario to calculate potential exposure of consumers to menthol and carvone, and since that the components of the additive are considered safe for their use as food and feed flavourings, the FEEDAP Panel concludes that the use of the additive in animal nutrition is considered safe for consumers. The FEEDAP Panel considered that exposure of users by inhalation is unlikely, but cannot conclude on the effects of Biomin(®)DC‐P on skin and eyes. The use of Biomin(®)DC‐P is not expected to pose a risk for the environment. Biomin(®)DC‐P has a potential to increase the growth performance of chickens for fattening when incorporated into feed at a minimum application rate of 65 mg/kg complete feed; the conclusion can be extended to chickens reared for laying and extrapolated to minor poultry species reared up to the point of lay. John Wiley and Sons Inc. 2019-06-11 /pmc/articles/PMC7009287/ /pubmed/32626346 http://dx.doi.org/10.2903/j.efsa.2019.5724 Text en © 2019 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
de Lourdes Bastos, Maria
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Chesson, Andrew
Gropp, Jürgen
Martelli, Giovanna
Renshaw, Derek
López‐Gálvez, Gloria
Mantovani, Alberto
Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay
title Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay
title_full Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay
title_fullStr Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay
title_full_unstemmed Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay
title_short Safety and efficacy of Biomin(®) DC‐P as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay
title_sort safety and efficacy of biomin(®) dc‐p as a zootechnical feed additive for chickens for fattening, chickens reared for laying and minor avian species to the point of lay
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009287/
https://www.ncbi.nlm.nih.gov/pubmed/32626346
http://dx.doi.org/10.2903/j.efsa.2019.5724
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