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Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Monteban(®) G100 for ducks. Monteban(®) G100, containing narasin, is intended for the prevention of...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009343/ https://www.ncbi.nlm.nih.gov/pubmed/32625745 http://dx.doi.org/10.2903/j.efsa.2018.5461 |
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author | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Aquilina, Gabriele Bories, Georges Brantom, Paul Cocconcelli, Pier Sandro Halle, Ingrid Kolar, Boris Wester, Pieter van Beelen, Patrick Holczknecht, Orsolya Vettori, Maria Vittoria Gropp, Jürgen |
author_facet | Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Aquilina, Gabriele Bories, Georges Brantom, Paul Cocconcelli, Pier Sandro Halle, Ingrid Kolar, Boris Wester, Pieter van Beelen, Patrick Holczknecht, Orsolya Vettori, Maria Vittoria Gropp, Jürgen |
collection | PubMed |
description | Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Monteban(®) G100 for ducks. Monteban(®) G100, containing narasin, is intended for the prevention of coccidiosis in ducks for fattening at a dose range of 60–70 mg/kg of complete feed. Narasin from Monteban(®) G100 is safe for ducks for fattening at a level of 70 mg/kg complete feed with a margin of safety of about 4. The FEEDAP Panel assumes that the residues in duck tissues would be of the same magnitude as those measured in the physiologically similar major species, chickens for fattening. The use of Monteban(®) G100 at a maximum concentration of 70 mg/kg complete feed for ducks for fattening is safe for the consumer without applying a withdrawal period, provided the maximum residue limit (MRL) of 50 μg narasin/kg for all wet tissues would not be exceeded. Monteban(®) G100 is irritant to the eyes but not to the skin. It has the potential to induce skin sensitisation. The acute systemic toxicity following dermal application is low. Inhalation exposure would pose a risk to persons handling the additive. Narasin, when used as feed additive for ducks for fattening at 70 mg/kg feed, is not expected to pose a risk to the environment. The risk for sediment compartment cannot be assessed. Narasin is not considered to have a bioaccumulation potential. Insufficient data were provided to allow a conclusion on the efficacy of Monteban(®) G100 in ducks. |
format | Online Article Text |
id | pubmed-7009343 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70093432020-07-02 Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Aquilina, Gabriele Bories, Georges Brantom, Paul Cocconcelli, Pier Sandro Halle, Ingrid Kolar, Boris Wester, Pieter van Beelen, Patrick Holczknecht, Orsolya Vettori, Maria Vittoria Gropp, Jürgen EFSA J Scientific Opinion Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Monteban(®) G100 for ducks. Monteban(®) G100, containing narasin, is intended for the prevention of coccidiosis in ducks for fattening at a dose range of 60–70 mg/kg of complete feed. Narasin from Monteban(®) G100 is safe for ducks for fattening at a level of 70 mg/kg complete feed with a margin of safety of about 4. The FEEDAP Panel assumes that the residues in duck tissues would be of the same magnitude as those measured in the physiologically similar major species, chickens for fattening. The use of Monteban(®) G100 at a maximum concentration of 70 mg/kg complete feed for ducks for fattening is safe for the consumer without applying a withdrawal period, provided the maximum residue limit (MRL) of 50 μg narasin/kg for all wet tissues would not be exceeded. Monteban(®) G100 is irritant to the eyes but not to the skin. It has the potential to induce skin sensitisation. The acute systemic toxicity following dermal application is low. Inhalation exposure would pose a risk to persons handling the additive. Narasin, when used as feed additive for ducks for fattening at 70 mg/kg feed, is not expected to pose a risk to the environment. The risk for sediment compartment cannot be assessed. Narasin is not considered to have a bioaccumulation potential. Insufficient data were provided to allow a conclusion on the efficacy of Monteban(®) G100 in ducks. John Wiley and Sons Inc. 2018-11-21 /pmc/articles/PMC7009343/ /pubmed/32625745 http://dx.doi.org/10.2903/j.efsa.2018.5461 Text en © 2018 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Aquilina, Gabriele Bories, Georges Brantom, Paul Cocconcelli, Pier Sandro Halle, Ingrid Kolar, Boris Wester, Pieter van Beelen, Patrick Holczknecht, Orsolya Vettori, Maria Vittoria Gropp, Jürgen Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening |
title | Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening |
title_full | Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening |
title_fullStr | Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening |
title_full_unstemmed | Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening |
title_short | Safety and efficacy of Monteban(®) G100 (narasin) for ducks for fattening |
title_sort | safety and efficacy of monteban(®) g100 (narasin) for ducks for fattening |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009343/ https://www.ncbi.nlm.nih.gov/pubmed/32625745 http://dx.doi.org/10.2903/j.efsa.2018.5461 |
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