Cargando…

Modification of the existing maximum residue levels for difenoconazole in various crops

In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant BASF SE submitted a request to the competent national authority in the United Kingdom to modify the existing maximum residue levels (MRLs) for the active substance difenoconazole in various crops. The data submitted in suppor...

Descripción completa

Detalles Bibliográficos
Autores principales: Brancato, Alba, Brocca, Daniela, De Lentdecker, Chloe, Erdos, Zoltan, Ferreira, Lucien, Greco, Luna, Janossy, Judit, Jarrah, Samira, Kardassi, Dimitra, Leuschner, Renata, Lythgo, Christopher, Medina, Paula, Miron, Ileana, Molnar, Tunde, Nougadere, Alexandre, Pedersen, Ragnor, Reich, Hermine, Sacchi, Angela, Santos, Miguel, Stanek, Alois, Sturma, Juergen, Tarazona, Jose, Theobald, Anne, Vagenende, Benedicte, Verani, Alessia, Villamar‐Bouza, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009345/
https://www.ncbi.nlm.nih.gov/pubmed/32625688
http://dx.doi.org/10.2903/j.efsa.2018.5143
_version_ 1783495645227646976
author Brancato, Alba
Brocca, Daniela
De Lentdecker, Chloe
Erdos, Zoltan
Ferreira, Lucien
Greco, Luna
Janossy, Judit
Jarrah, Samira
Kardassi, Dimitra
Leuschner, Renata
Lythgo, Christopher
Medina, Paula
Miron, Ileana
Molnar, Tunde
Nougadere, Alexandre
Pedersen, Ragnor
Reich, Hermine
Sacchi, Angela
Santos, Miguel
Stanek, Alois
Sturma, Juergen
Tarazona, Jose
Theobald, Anne
Vagenende, Benedicte
Verani, Alessia
Villamar‐Bouza, Laura
author_facet Brancato, Alba
Brocca, Daniela
De Lentdecker, Chloe
Erdos, Zoltan
Ferreira, Lucien
Greco, Luna
Janossy, Judit
Jarrah, Samira
Kardassi, Dimitra
Leuschner, Renata
Lythgo, Christopher
Medina, Paula
Miron, Ileana
Molnar, Tunde
Nougadere, Alexandre
Pedersen, Ragnor
Reich, Hermine
Sacchi, Angela
Santos, Miguel
Stanek, Alois
Sturma, Juergen
Tarazona, Jose
Theobald, Anne
Vagenende, Benedicte
Verani, Alessia
Villamar‐Bouza, Laura
collection PubMed
description In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant BASF SE submitted a request to the competent national authority in the United Kingdom to modify the existing maximum residue levels (MRLs) for the active substance difenoconazole in various crops. The data submitted in support of the request were found to be sufficient to derive MRL proposals for all crops under consideration. Adequate analytical methods for enforcement are available to control the residues of difenoconazole in plant matrices under consideration. The estimated long‐term and short‐term intake to residues of difenoconazole resulting from the existing and the intended uses did not exceed the toxicological reference values established for the active substance difenoconazole. The consumer exposure assessment has to be considered provisional as the impact of a potentially different isomer composition in the residues of difenoconazole on this risk assessment is currently unknown and has to be reconsidered when data on possible preferential metabolism/degradation of the four stereo isomers of difenoconazole in plants is available and guidance on a risk assessment approach for residues containing isomers is implemented.
format Online
Article
Text
id pubmed-7009345
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-70093452020-07-02 Modification of the existing maximum residue levels for difenoconazole in various crops Brancato, Alba Brocca, Daniela De Lentdecker, Chloe Erdos, Zoltan Ferreira, Lucien Greco, Luna Janossy, Judit Jarrah, Samira Kardassi, Dimitra Leuschner, Renata Lythgo, Christopher Medina, Paula Miron, Ileana Molnar, Tunde Nougadere, Alexandre Pedersen, Ragnor Reich, Hermine Sacchi, Angela Santos, Miguel Stanek, Alois Sturma, Juergen Tarazona, Jose Theobald, Anne Vagenende, Benedicte Verani, Alessia Villamar‐Bouza, Laura EFSA J Reasoned Opinion In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant BASF SE submitted a request to the competent national authority in the United Kingdom to modify the existing maximum residue levels (MRLs) for the active substance difenoconazole in various crops. The data submitted in support of the request were found to be sufficient to derive MRL proposals for all crops under consideration. Adequate analytical methods for enforcement are available to control the residues of difenoconazole in plant matrices under consideration. The estimated long‐term and short‐term intake to residues of difenoconazole resulting from the existing and the intended uses did not exceed the toxicological reference values established for the active substance difenoconazole. The consumer exposure assessment has to be considered provisional as the impact of a potentially different isomer composition in the residues of difenoconazole on this risk assessment is currently unknown and has to be reconsidered when data on possible preferential metabolism/degradation of the four stereo isomers of difenoconazole in plants is available and guidance on a risk assessment approach for residues containing isomers is implemented. John Wiley and Sons Inc. 2018-01-19 /pmc/articles/PMC7009345/ /pubmed/32625688 http://dx.doi.org/10.2903/j.efsa.2018.5143 Text en © 2018 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Reasoned Opinion
Brancato, Alba
Brocca, Daniela
De Lentdecker, Chloe
Erdos, Zoltan
Ferreira, Lucien
Greco, Luna
Janossy, Judit
Jarrah, Samira
Kardassi, Dimitra
Leuschner, Renata
Lythgo, Christopher
Medina, Paula
Miron, Ileana
Molnar, Tunde
Nougadere, Alexandre
Pedersen, Ragnor
Reich, Hermine
Sacchi, Angela
Santos, Miguel
Stanek, Alois
Sturma, Juergen
Tarazona, Jose
Theobald, Anne
Vagenende, Benedicte
Verani, Alessia
Villamar‐Bouza, Laura
Modification of the existing maximum residue levels for difenoconazole in various crops
title Modification of the existing maximum residue levels for difenoconazole in various crops
title_full Modification of the existing maximum residue levels for difenoconazole in various crops
title_fullStr Modification of the existing maximum residue levels for difenoconazole in various crops
title_full_unstemmed Modification of the existing maximum residue levels for difenoconazole in various crops
title_short Modification of the existing maximum residue levels for difenoconazole in various crops
title_sort modification of the existing maximum residue levels for difenoconazole in various crops
topic Reasoned Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009345/
https://www.ncbi.nlm.nih.gov/pubmed/32625688
http://dx.doi.org/10.2903/j.efsa.2018.5143
work_keys_str_mv AT modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT brancatoalba modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT broccadaniela modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT delentdeckerchloe modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT erdoszoltan modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT ferreiralucien modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT grecoluna modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT janossyjudit modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT jarrahsamira modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT kardassidimitra modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT leuschnerrenata modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT lythgochristopher modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT medinapaula modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT mironileana modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT molnartunde modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT nougaderealexandre modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT pedersenragnor modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT reichhermine modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT sacchiangela modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT santosmiguel modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT stanekalois modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT sturmajuergen modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT tarazonajose modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT theobaldanne modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT vagenendebenedicte modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT veranialessia modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops
AT villamarbouzalaura modificationoftheexistingmaximumresiduelevelsfordifenoconazoleinvariouscrops