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Safety of zinc chelate of methionine sulfate for the target species

Zinc chelate of methionine sulfate is intended to be used as a nutritional additive (functional group: compounds of trace elements). The additive is zinc chelated with methionine in a molar ratio 1:1. It is intended to supply zinc as a nutritional additive to all animal species/categories. In 2017,...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Kouba, Maryline, Kos Durjava, Mojca, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Flachowsky, Gerhard, Cubadda, Francesco, López‐Gálvez, Gloria, Mantovani, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009465/
https://www.ncbi.nlm.nih.gov/pubmed/32625736
http://dx.doi.org/10.2903/j.efsa.2018.5463
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Flachowsky, Gerhard
Cubadda, Francesco
López‐Gálvez, Gloria
Mantovani, Alberto
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Flachowsky, Gerhard
Cubadda, Francesco
López‐Gálvez, Gloria
Mantovani, Alberto
collection PubMed
description Zinc chelate of methionine sulfate is intended to be used as a nutritional additive (functional group: compounds of trace elements). The additive is zinc chelated with methionine in a molar ratio 1:1. It is intended to supply zinc as a nutritional additive to all animal species/categories. In 2017, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) adopted an opinion on the safety and efficacy of zinc chelate of methionine sulfate for all animal species. In that opinion, the Panel could not conclude on the safety of the additive for the target species. The Commission gave the applicant the possibility of submitting additional information to allow the FEEDAP Panel to complete its assessment. For this reason, additional data have been provided related to the safety of the additive for the target species and this new information is the subject of this opinion. The new tolerance study on chickens for fattening has been assessed; the results of this study indicate that the additive does not promote adverse effects in the birds as compared to an inorganic source of zinc (zinc oxide). The FEEDAP Panel concluded that the additive under assessment ‘zinc chelate of methionine sulfate’ is safe for chickens for fattening when used up to the maximum content of zinc in complete feed authorised in the EU; this conclusion is extended to all animal species.
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spelling pubmed-70094652020-07-02 Safety of zinc chelate of methionine sulfate for the target species Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Kouba, Maryline Kos Durjava, Mojca López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Flachowsky, Gerhard Cubadda, Francesco López‐Gálvez, Gloria Mantovani, Alberto EFSA J Scientific Opinion Zinc chelate of methionine sulfate is intended to be used as a nutritional additive (functional group: compounds of trace elements). The additive is zinc chelated with methionine in a molar ratio 1:1. It is intended to supply zinc as a nutritional additive to all animal species/categories. In 2017, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) adopted an opinion on the safety and efficacy of zinc chelate of methionine sulfate for all animal species. In that opinion, the Panel could not conclude on the safety of the additive for the target species. The Commission gave the applicant the possibility of submitting additional information to allow the FEEDAP Panel to complete its assessment. For this reason, additional data have been provided related to the safety of the additive for the target species and this new information is the subject of this opinion. The new tolerance study on chickens for fattening has been assessed; the results of this study indicate that the additive does not promote adverse effects in the birds as compared to an inorganic source of zinc (zinc oxide). The FEEDAP Panel concluded that the additive under assessment ‘zinc chelate of methionine sulfate’ is safe for chickens for fattening when used up to the maximum content of zinc in complete feed authorised in the EU; this conclusion is extended to all animal species. John Wiley and Sons Inc. 2018-10-24 /pmc/articles/PMC7009465/ /pubmed/32625736 http://dx.doi.org/10.2903/j.efsa.2018.5463 Text en © 2018 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Kouba, Maryline
Kos Durjava, Mojca
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Flachowsky, Gerhard
Cubadda, Francesco
López‐Gálvez, Gloria
Mantovani, Alberto
Safety of zinc chelate of methionine sulfate for the target species
title Safety of zinc chelate of methionine sulfate for the target species
title_full Safety of zinc chelate of methionine sulfate for the target species
title_fullStr Safety of zinc chelate of methionine sulfate for the target species
title_full_unstemmed Safety of zinc chelate of methionine sulfate for the target species
title_short Safety of zinc chelate of methionine sulfate for the target species
title_sort safety of zinc chelate of methionine sulfate for the target species
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009465/
https://www.ncbi.nlm.nih.gov/pubmed/32625736
http://dx.doi.org/10.2903/j.efsa.2018.5463
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