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Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species

The additive, ‘Zinc‐l‐selenomethionine’ (Zn‐l‐SeMet) is intended to be used as a source of selenium for all animal species. The applicant intends to market the active compound blended with inert carriers (Availa(®)Se). Zn‐l‐SeMet is a safe source of selenium for chickens for fattening; the conclusio...

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Autores principales: Rychen, Guido, Aquilina, Gabriele, Azimonti, Giovanna, Bampidis, Vasileios, Bastos, Maria de Lourdes, Bories, Georges, Chesson, Andrew, Cocconcelli, Pier Sandro, Flachowsky, Gerhard, Gropp, Jürgen, Kolar, Boris, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Mayo, Baltasar, Ramos, Fernando, Saarela, Maria, Villa, Roberto Edoardo, Wallace, Robert John, Wester, Pieter, Pechova, Alena, López‐Gálvez, Gloria, Mantovani, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009677/
https://www.ncbi.nlm.nih.gov/pubmed/32625833
http://dx.doi.org/10.2903/j.efsa.2018.5197
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author Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Mayo, Baltasar
Ramos, Fernando
Saarela, Maria
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Pechova, Alena
López‐Gálvez, Gloria
Mantovani, Alberto
author_facet Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Mayo, Baltasar
Ramos, Fernando
Saarela, Maria
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Pechova, Alena
López‐Gálvez, Gloria
Mantovani, Alberto
collection PubMed
description The additive, ‘Zinc‐l‐selenomethionine’ (Zn‐l‐SeMet) is intended to be used as a source of selenium for all animal species. The applicant intends to market the active compound blended with inert carriers (Availa(®)Se). Zn‐l‐SeMet is a safe source of selenium for chickens for fattening; the conclusion is extended to all animal species. Selenium from Zn‐l‐SeMet does not elicit any adverse effects not expected for a selenium compound. The use of Zn‐l‐SeMet in animal nutrition is expected to result in a similar increase in selenium deposition in animal tissues/products as that resulting from other sources of SeMet. The use of the additive up to the maximum selenium supplementation level established for other sources of organic selenium (0.2 mg/kg complete feed) and complying with the maximum authorised total selenium content is safe for consumers. The additive is hazardous upon inhalation; owing to the high dusting potential, persons handling Availa(®)Se are at risk by inhalation. Availa(®)Se is not an irritant to the skin. In the absence of data, no conclusion on the eye irritation and skin sensitisation can be drawn. The use of Zn‐l‐SeMet in feed does not pose an additional risk to the environment, compared with other sources of selenium for which it will substitute, as long as the maximum authorised content in complete feed is not exceeded. Zn‐l‐SeMet is an effective source of selenium in chickens for fattening and laying hens; this conclusion is extended to all animal species. The maximum contribution of zinc in total feed deriving from the use of the additive (< 0.2 mg Zn/kg feed) is considered low and does not need any safety assessment except for users.
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spelling pubmed-70096772020-07-02 Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Cocconcelli, Pier Sandro Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Mayo, Baltasar Ramos, Fernando Saarela, Maria Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Pechova, Alena López‐Gálvez, Gloria Mantovani, Alberto EFSA J Scientific Opinion The additive, ‘Zinc‐l‐selenomethionine’ (Zn‐l‐SeMet) is intended to be used as a source of selenium for all animal species. The applicant intends to market the active compound blended with inert carriers (Availa(®)Se). Zn‐l‐SeMet is a safe source of selenium for chickens for fattening; the conclusion is extended to all animal species. Selenium from Zn‐l‐SeMet does not elicit any adverse effects not expected for a selenium compound. The use of Zn‐l‐SeMet in animal nutrition is expected to result in a similar increase in selenium deposition in animal tissues/products as that resulting from other sources of SeMet. The use of the additive up to the maximum selenium supplementation level established for other sources of organic selenium (0.2 mg/kg complete feed) and complying with the maximum authorised total selenium content is safe for consumers. The additive is hazardous upon inhalation; owing to the high dusting potential, persons handling Availa(®)Se are at risk by inhalation. Availa(®)Se is not an irritant to the skin. In the absence of data, no conclusion on the eye irritation and skin sensitisation can be drawn. The use of Zn‐l‐SeMet in feed does not pose an additional risk to the environment, compared with other sources of selenium for which it will substitute, as long as the maximum authorised content in complete feed is not exceeded. Zn‐l‐SeMet is an effective source of selenium in chickens for fattening and laying hens; this conclusion is extended to all animal species. The maximum contribution of zinc in total feed deriving from the use of the additive (< 0.2 mg Zn/kg feed) is considered low and does not need any safety assessment except for users. John Wiley and Sons Inc. 2018-03-08 /pmc/articles/PMC7009677/ /pubmed/32625833 http://dx.doi.org/10.2903/j.efsa.2018.5197 Text en © 2018 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Mayo, Baltasar
Ramos, Fernando
Saarela, Maria
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Pechova, Alena
López‐Gálvez, Gloria
Mantovani, Alberto
Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species
title Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species
title_full Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species
title_fullStr Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species
title_full_unstemmed Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species
title_short Safety and efficacy of Zinc‐l‐Selenomethionine as feed additive for all animal species
title_sort safety and efficacy of zinc‐l‐selenomethionine as feed additive for all animal species
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009677/
https://www.ncbi.nlm.nih.gov/pubmed/32625833
http://dx.doi.org/10.2903/j.efsa.2018.5197
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