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Bauerane Induces S-Phase Cell Cycle Arrest, Apoptosis, and Inhibition of Proliferation of A549 Human Lung Cancer Cells Through the Phosphoinositide 3-Kinase (PI3K)/AKT and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway

BACKGROUND: Bauerane is a triterpenoid derived from the dandelion root (Taraxacum officinale). This study aimed to investigate the effects of bauerane on cell proliferation of A549 human lung cancer cells and the molecular mechanisms involved. MATERIAL/METHODS: A549 human lung adenocarcinoma cells a...

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Detalles Bibliográficos
Autores principales: Chen, Qin, Wang, Ming, Shen, Chengji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009776/
https://www.ncbi.nlm.nih.gov/pubmed/32005795
http://dx.doi.org/10.12659/MSM.919558

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