Cargando…

Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on VevoVitall(®) (benzoic acid) as a feed additive for minor porcine species, when used as zootechnical additive at a maximu...

Descripción completa

Detalles Bibliográficos
Autores principales: Rychen, Guido, Aquilina, Gabriele, Azimonti, Giovanna, Bampidis, Vasileios, Bastos, Maria de Lourdes, Bories, Georges, Chesson, Andrew, Cocconcelli, Pier Sandro, Flachowsky, Gerhard, Gropp, Jürgen, Kolar, Boris, Kouba, Maryline, López‐Alonso, Marta, Mantovani, Alberto, Mayo, Baltasar, Ramos, Fernando, Saarela, Maria, Villa, Roberto Edoardo, Wallace, Robert John, Wester, Pieter, Martelli, Giovanna, Renshaw, Derek, López‐Gálvez, Gloria, López Puente, Secundino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009800/
https://www.ncbi.nlm.nih.gov/pubmed/32625315
http://dx.doi.org/10.2903/j.efsa.2017.5026
_version_ 1783495744094732288
author Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
Mantovani, Alberto
Mayo, Baltasar
Ramos, Fernando
Saarela, Maria
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Martelli, Giovanna
Renshaw, Derek
López‐Gálvez, Gloria
López Puente, Secundino
author_facet Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
Mantovani, Alberto
Mayo, Baltasar
Ramos, Fernando
Saarela, Maria
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Martelli, Giovanna
Renshaw, Derek
López‐Gálvez, Gloria
López Puente, Secundino
collection PubMed
description Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on VevoVitall(®) (benzoic acid) as a feed additive for minor porcine species, when used as zootechnical additive at a maximum level of 5,000 mg/kg complete feed. The safety and efficacy of the additive had been evaluated by the FEEDAP Panel on weaned piglets (at the maximum supplementation level of 5,000 mg/kg complete feed) and pigs for fattening and pigs for reproduction (at the maximum level of 10,000 mg/kg complete feed). Subsequent to EFSA's assessments, the additive has been authorised for use in feed of weaned piglets, pigs for fattening and sows. To the knowledge of the FEEDAP Panel, there was no new information that might modify its previous assessments on VevoVitall(®) concerning safety for consumers and the environment; therefore, this opinion focused only on the safety of the target animals and the efficacy of the product. The FEEDAP Panel concluded that VevoVitall(®) is safe at the supplementation level of 5,000 mg/kg complete feed for minor porcine species for fattening and for reproduction; the FEEDAP could not conclude on the safety of the additive for weaned minor porcine species. VevoVitall(®) does not represent a risk for the consumer and the environment. VevoVitall(®) does not pose a risk by inhalation to users and is not skin sensitiser, but is a skin irritant and a severe eye irritant. VevoVitall(®) has the potential to decrease the urinary pH in minor porcine species at the dose of 5,000 mg/kg complete feed. A remark on the relevance of the claim has been posted by the Panel.
format Online
Article
Text
id pubmed-7009800
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-70098002020-07-02 Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Cocconcelli, Pier Sandro Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López‐Alonso, Marta Mantovani, Alberto Mayo, Baltasar Ramos, Fernando Saarela, Maria Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Martelli, Giovanna Renshaw, Derek López‐Gálvez, Gloria López Puente, Secundino EFSA J Scientific Opinion Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on VevoVitall(®) (benzoic acid) as a feed additive for minor porcine species, when used as zootechnical additive at a maximum level of 5,000 mg/kg complete feed. The safety and efficacy of the additive had been evaluated by the FEEDAP Panel on weaned piglets (at the maximum supplementation level of 5,000 mg/kg complete feed) and pigs for fattening and pigs for reproduction (at the maximum level of 10,000 mg/kg complete feed). Subsequent to EFSA's assessments, the additive has been authorised for use in feed of weaned piglets, pigs for fattening and sows. To the knowledge of the FEEDAP Panel, there was no new information that might modify its previous assessments on VevoVitall(®) concerning safety for consumers and the environment; therefore, this opinion focused only on the safety of the target animals and the efficacy of the product. The FEEDAP Panel concluded that VevoVitall(®) is safe at the supplementation level of 5,000 mg/kg complete feed for minor porcine species for fattening and for reproduction; the FEEDAP could not conclude on the safety of the additive for weaned minor porcine species. VevoVitall(®) does not represent a risk for the consumer and the environment. VevoVitall(®) does not pose a risk by inhalation to users and is not skin sensitiser, but is a skin irritant and a severe eye irritant. VevoVitall(®) has the potential to decrease the urinary pH in minor porcine species at the dose of 5,000 mg/kg complete feed. A remark on the relevance of the claim has been posted by the Panel. John Wiley and Sons Inc. 2017-10-17 /pmc/articles/PMC7009800/ /pubmed/32625315 http://dx.doi.org/10.2903/j.efsa.2017.5026 Text en © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
Mantovani, Alberto
Mayo, Baltasar
Ramos, Fernando
Saarela, Maria
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Martelli, Giovanna
Renshaw, Derek
López‐Gálvez, Gloria
López Puente, Secundino
Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species
title Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species
title_full Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species
title_fullStr Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species
title_full_unstemmed Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species
title_short Safety and efficacy of VevoVitall(®) (benzoic acid) as feed additive for minor porcine species
title_sort safety and efficacy of vevovitall(®) (benzoic acid) as feed additive for minor porcine species
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009800/
https://www.ncbi.nlm.nih.gov/pubmed/32625315
http://dx.doi.org/10.2903/j.efsa.2017.5026
work_keys_str_mv AT safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT rychenguido safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT aquilinagabriele safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT azimontigiovanna safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT bampidisvasileios safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT bastosmariadelourdes safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT boriesgeorges safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT chessonandrew safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT cocconcellipiersandro safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT flachowskygerhard safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT groppjurgen safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT kolarboris safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT koubamaryline safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT lopezalonsomarta safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT mantovanialberto safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT mayobaltasar safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT ramosfernando safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT saarelamaria safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT villarobertoedoardo safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT wallacerobertjohn safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT westerpieter safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT martelligiovanna safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT renshawderek safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT lopezgalvezgloria safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies
AT lopezpuentesecundino safetyandefficacyofvevovitallbenzoicacidasfeedadditiveforminorporcinespecies