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Safety of l‐tryptophan technically pure, produced by Escherichia coli CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH
l‐Tryptophan, technically pure, is a feed additive produced by fermentation with a genetically modified strain of Escherichia coli. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) of EFSA, issued two opinions on the safety and efficacy of the product, in which it could...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009801/ https://www.ncbi.nlm.nih.gov/pubmed/32625427 http://dx.doi.org/10.2903/j.efsa.2017.4705 |
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| author | Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Mayo, Baltasar Ramos, Fernando Saarela, Maria Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Glandorf, Boet Herman, Lieve Kärenlampi, Sirpa Aguilera, Jaime Cocconcelli, Pier Sandro |
| author_facet | Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Mayo, Baltasar Ramos, Fernando Saarela, Maria Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Glandorf, Boet Herman, Lieve Kärenlampi, Sirpa Aguilera, Jaime Cocconcelli, Pier Sandro |
| collection | PubMed |
| description | l‐Tryptophan, technically pure, is a feed additive produced by fermentation with a genetically modified strain of Escherichia coli. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) of EFSA, issued two opinions on the safety and efficacy of the product, in which it could not conclude on the safety of this additive for target animals, consumer, user and the environment, due to the insufficient characterisation of the genetic modification. The European Commission asked the Authority to deliver an opinion on the safety of l‐tryptophan, technically pure, as a nutritional additive for all animal species based on additional data submitted by the applicant. Based on new information provided on the genetic modification, including the presence/absence of antibiotic resistance genes in the production strain, the FEEDAP Panel concludes that the l‐tryptophan is safe for target animals, consumers, users and the environment. |
| format | Online Article Text |
| id | pubmed-7009801 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-70098012020-07-02 Safety of l‐tryptophan technically pure, produced by Escherichia coli CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Mayo, Baltasar Ramos, Fernando Saarela, Maria Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Glandorf, Boet Herman, Lieve Kärenlampi, Sirpa Aguilera, Jaime Cocconcelli, Pier Sandro EFSA J Scientific Opinion l‐Tryptophan, technically pure, is a feed additive produced by fermentation with a genetically modified strain of Escherichia coli. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) of EFSA, issued two opinions on the safety and efficacy of the product, in which it could not conclude on the safety of this additive for target animals, consumer, user and the environment, due to the insufficient characterisation of the genetic modification. The European Commission asked the Authority to deliver an opinion on the safety of l‐tryptophan, technically pure, as a nutritional additive for all animal species based on additional data submitted by the applicant. Based on new information provided on the genetic modification, including the presence/absence of antibiotic resistance genes in the production strain, the FEEDAP Panel concludes that the l‐tryptophan is safe for target animals, consumers, users and the environment. John Wiley and Sons Inc. 2017-03-06 /pmc/articles/PMC7009801/ /pubmed/32625427 http://dx.doi.org/10.2903/j.efsa.2017.4705 Text en © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
| spellingShingle | Scientific Opinion Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Mayo, Baltasar Ramos, Fernando Saarela, Maria Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Glandorf, Boet Herman, Lieve Kärenlampi, Sirpa Aguilera, Jaime Cocconcelli, Pier Sandro Safety of l‐tryptophan technically pure, produced by Escherichia coli CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH |
| title | Safety of l‐tryptophan technically pure, produced by Escherichia coli
CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH |
| title_full | Safety of l‐tryptophan technically pure, produced by Escherichia coli
CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH |
| title_fullStr | Safety of l‐tryptophan technically pure, produced by Escherichia coli
CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH |
| title_full_unstemmed | Safety of l‐tryptophan technically pure, produced by Escherichia coli
CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH |
| title_short | Safety of l‐tryptophan technically pure, produced by Escherichia coli
CGMCC 3667, for all animal species based on a dossier submitted by GBT Europe GmbH |
| title_sort | safety of l‐tryptophan technically pure, produced by escherichia coli
cgmcc 3667, for all animal species based on a dossier submitted by gbt europe gmbh |
| topic | Scientific Opinion |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009801/ https://www.ncbi.nlm.nih.gov/pubmed/32625427 http://dx.doi.org/10.2903/j.efsa.2017.4705 |
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