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Safety and efficacy of Levucell(®) SC (Saccharomyces cerevisiae CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Levucell(®) SC for dairy cows, cattle for fattening, all minor ruminant species and camelids....
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009926/ https://www.ncbi.nlm.nih.gov/pubmed/32625596 http://dx.doi.org/10.2903/j.efsa.2017.4944 |
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author | Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Cocconcelli, Pier Sandro Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López Puente, Secundino López‐Alonso, Marta Mantovani, Alberto Mayo, Baltasar Ramos, Fernando Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Brozzi, Rosella Saarela, Maria |
author_facet | Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Cocconcelli, Pier Sandro Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López Puente, Secundino López‐Alonso, Marta Mantovani, Alberto Mayo, Baltasar Ramos, Fernando Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Brozzi, Rosella Saarela, Maria |
collection | PubMed |
description | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Levucell(®) SC for dairy cows, cattle for fattening, all minor ruminant species and camelids. The additive consists of viable cells of a strain of Saccharomyces cerevisae and is sold in three formulations. The FEEDAP Panel considers that the three available formulations are equivalent when used to deliver the same dose. The active agent fulfils the requirements of the qualified presumption of safety approach to the assessment of safety and since no concerns are expected from other components, Levucell(®) SC can be presumed safe for target animals, consumers of products from treated animals and the environment. Levucell(®) SC is not a skin irritant or sensitiser but is an eye irritant. Inhalation exposure is unlikely. Encapsulation is not expected to introduce hazards for users. The FEEDAP Panel is not in the position to conclude on the efficacy of Levucell(®) SC for dairy cows, minor dairy ruminant species or dairy camelids. Levucell(®) SC has a potential to improve the performance of cattle raised for fattening when supplied at a minimum dose of 8 × 10(9) CFU/head and day which would approximate to 6 × 10(8) CFU/kg complete feed. This conclusion is extended to minor ruminant species and camelids reared for meat production at the same minimum dose of 6 × 10(8) CFU/kg complete feed. |
format | Online Article Text |
id | pubmed-7009926 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-70099262020-07-02 Safety and efficacy of Levucell(®) SC (Saccharomyces cerevisiae CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Cocconcelli, Pier Sandro Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López Puente, Secundino López‐Alonso, Marta Mantovani, Alberto Mayo, Baltasar Ramos, Fernando Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Brozzi, Rosella Saarela, Maria EFSA J Scientific Opinion Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Levucell(®) SC for dairy cows, cattle for fattening, all minor ruminant species and camelids. The additive consists of viable cells of a strain of Saccharomyces cerevisae and is sold in three formulations. The FEEDAP Panel considers that the three available formulations are equivalent when used to deliver the same dose. The active agent fulfils the requirements of the qualified presumption of safety approach to the assessment of safety and since no concerns are expected from other components, Levucell(®) SC can be presumed safe for target animals, consumers of products from treated animals and the environment. Levucell(®) SC is not a skin irritant or sensitiser but is an eye irritant. Inhalation exposure is unlikely. Encapsulation is not expected to introduce hazards for users. The FEEDAP Panel is not in the position to conclude on the efficacy of Levucell(®) SC for dairy cows, minor dairy ruminant species or dairy camelids. Levucell(®) SC has a potential to improve the performance of cattle raised for fattening when supplied at a minimum dose of 8 × 10(9) CFU/head and day which would approximate to 6 × 10(8) CFU/kg complete feed. This conclusion is extended to minor ruminant species and camelids reared for meat production at the same minimum dose of 6 × 10(8) CFU/kg complete feed. John Wiley and Sons Inc. 2017-07-19 /pmc/articles/PMC7009926/ /pubmed/32625596 http://dx.doi.org/10.2903/j.efsa.2017.4944 Text en © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made. |
spellingShingle | Scientific Opinion Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Cocconcelli, Pier Sandro Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López Puente, Secundino López‐Alonso, Marta Mantovani, Alberto Mayo, Baltasar Ramos, Fernando Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Brozzi, Rosella Saarela, Maria Safety and efficacy of Levucell(®) SC (Saccharomyces cerevisiae CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids |
title | Safety and efficacy of Levucell(®)
SC (Saccharomyces cerevisiae
CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids |
title_full | Safety and efficacy of Levucell(®)
SC (Saccharomyces cerevisiae
CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids |
title_fullStr | Safety and efficacy of Levucell(®)
SC (Saccharomyces cerevisiae
CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids |
title_full_unstemmed | Safety and efficacy of Levucell(®)
SC (Saccharomyces cerevisiae
CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids |
title_short | Safety and efficacy of Levucell(®)
SC (Saccharomyces cerevisiae
CNCM I‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids |
title_sort | safety and efficacy of levucell(®)
sc (saccharomyces cerevisiae
cncm i‐1077) as a feed additive for dairy cows, cattle for fattening, minor ruminant species and camelids |
topic | Scientific Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7009926/ https://www.ncbi.nlm.nih.gov/pubmed/32625596 http://dx.doi.org/10.2903/j.efsa.2017.4944 |
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