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Chemoenzymatic conversion of amides to enantioenriched alcohols in aqueous medium

One-pot reactions that combine non-enzymatic and biocatalytic transformations represent an emerging strategy in chemical synthesis. Some of the most powerful chemoenzymatic methodologies, although uncommon, are those that form a carbon–carbon (C–C) bond and a stereocenter at one of the reacting carb...

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Detalles Bibliográficos
Autores principales: Dander, Jacob E., Giroud, Maude, Racine, Sophie, Darzi, Evan R., Alvizo, Oscar, Entwistle, David, Garg, Neil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010078/
https://www.ncbi.nlm.nih.gov/pubmed/32042928
http://dx.doi.org/10.1038/s42004-019-0182-8

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