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Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed was asked to deliver a scientific opinion on the safety and efficacy of a strain of Lactobacillus casei when used as a technological additive intended to improve ensiling at a prop...

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Autores principales: Rychen, Guido, Aquilina, Gabriele, Azimonti, Giovanna, Bampidis, Vasileios, Bastos, Maria de Lourdes, Bories, Georges, Chesson, Andrew, Cocconcelli, Pier Sandro, Flachowsky, Gerhard, Gropp, Jürgen, Kolar, Boris, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Mantovani, Alberto, Ramos, Fernando, Villa, Roberto Edoardo, Wallace, Robert John, Wester, Pieter, Brozzi, Rosella, Saarela, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010089/
https://www.ncbi.nlm.nih.gov/pubmed/32625426
http://dx.doi.org/10.2903/j.efsa.2017.4703
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author Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Mantovani, Alberto
Ramos, Fernando
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Brozzi, Rosella
Saarela, Maria
author_facet Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Mantovani, Alberto
Ramos, Fernando
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Brozzi, Rosella
Saarela, Maria
collection PubMed
description Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed was asked to deliver a scientific opinion on the safety and efficacy of a strain of Lactobacillus casei when used as a technological additive intended to improve ensiling at a proposed application rate of 1 × 10(8) CFU (when used alone) or 5 × 10(7) CFU (when used in combination) kg/fresh matter. The species L. casei is considered by EFSA to be suitable for the qualified presumption of safety approach to safety assessment and not to require specific demonstration of safety other than the absence of resistance to antibiotics of human and veterinary significance. As the identity of the strain was clearly established and as no antibiotic resistance was detected, the use of the strain in the production of silage is presumed safe for livestock species, consumers of products from animals fed treated silage and the environment. In the absence of data, no conclusion can be drawn on the skin and eye irritancy of the additive. The additive should be considered to have the potential to be a respiratory sensitiser. Five studies with laboratory‐scale silos were made using forage of differing water‐soluble carbohydrate content. Replicate silos containing forages treated at the proposed application rate were compared to identical silos containing the same but untreated forage. The mini‐silos were stored for 90 days at 20–24°C. At the end of the ensiling period, the content of the silos was analysed and dry matter losses determined. Results showed that the L. casei strain applied at a minimum dose of 5 × 10(7) CFU/kg has the potential to improve the production of silage from easy and moderately difficult to ensile forage species by reducing dry matter loss and enhancing protein preservation.
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spelling pubmed-70100892020-07-02 Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species Rychen, Guido Aquilina, Gabriele Azimonti, Giovanna Bampidis, Vasileios Bastos, Maria de Lourdes Bories, Georges Chesson, Andrew Cocconcelli, Pier Sandro Flachowsky, Gerhard Gropp, Jürgen Kolar, Boris Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Mantovani, Alberto Ramos, Fernando Villa, Roberto Edoardo Wallace, Robert John Wester, Pieter Brozzi, Rosella Saarela, Maria EFSA J Scientific Opinion Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed was asked to deliver a scientific opinion on the safety and efficacy of a strain of Lactobacillus casei when used as a technological additive intended to improve ensiling at a proposed application rate of 1 × 10(8) CFU (when used alone) or 5 × 10(7) CFU (when used in combination) kg/fresh matter. The species L. casei is considered by EFSA to be suitable for the qualified presumption of safety approach to safety assessment and not to require specific demonstration of safety other than the absence of resistance to antibiotics of human and veterinary significance. As the identity of the strain was clearly established and as no antibiotic resistance was detected, the use of the strain in the production of silage is presumed safe for livestock species, consumers of products from animals fed treated silage and the environment. In the absence of data, no conclusion can be drawn on the skin and eye irritancy of the additive. The additive should be considered to have the potential to be a respiratory sensitiser. Five studies with laboratory‐scale silos were made using forage of differing water‐soluble carbohydrate content. Replicate silos containing forages treated at the proposed application rate were compared to identical silos containing the same but untreated forage. The mini‐silos were stored for 90 days at 20–24°C. At the end of the ensiling period, the content of the silos was analysed and dry matter losses determined. Results showed that the L. casei strain applied at a minimum dose of 5 × 10(7) CFU/kg has the potential to improve the production of silage from easy and moderately difficult to ensile forage species by reducing dry matter loss and enhancing protein preservation. John Wiley and Sons Inc. 2017-03-02 /pmc/articles/PMC7010089/ /pubmed/32625426 http://dx.doi.org/10.2903/j.efsa.2017.4703 Text en © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Rychen, Guido
Aquilina, Gabriele
Azimonti, Giovanna
Bampidis, Vasileios
Bastos, Maria de Lourdes
Bories, Georges
Chesson, Andrew
Cocconcelli, Pier Sandro
Flachowsky, Gerhard
Gropp, Jürgen
Kolar, Boris
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Mantovani, Alberto
Ramos, Fernando
Villa, Roberto Edoardo
Wallace, Robert John
Wester, Pieter
Brozzi, Rosella
Saarela, Maria
Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species
title Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species
title_full Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species
title_fullStr Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species
title_full_unstemmed Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species
title_short Safety and efficacy of Lactobacillus casei DSM 28872 as a silage additive for all animal species
title_sort safety and efficacy of lactobacillus casei dsm 28872 as a silage additive for all animal species
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010089/
https://www.ncbi.nlm.nih.gov/pubmed/32625426
http://dx.doi.org/10.2903/j.efsa.2017.4703
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