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Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005

According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance fenbutatin oxide. Although this active substance is no longer authorised within the EU due to the lack of toxicologic...

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Autores principales: Brancato, Alba, Brocca, Daniela, De Lentdecker, Chloe, Erdos, Zoltan, Ferreira, Lucien, Greco, Luna, Jarrah, Samira, Kardassi, Dimitra, Leuschner, Renata, Lythgo, Christopher, Medina, Paula, Miron, Ileana, Molnar, Tunde, Nougadere, Alexandre, Pedersen, Ragnor, Reich, Hermine, Sacchi, Angela, Santos, Miguel, Stanek, Alois, Sturma, Juergen, Tarazona, Jose, Theobald, Anne, Vagenende, Benedicte, Verani, Alessia, Villamar‐Bouza, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010134/
https://www.ncbi.nlm.nih.gov/pubmed/32625377
http://dx.doi.org/10.2903/j.efsa.2017.5091
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author Brancato, Alba
Brocca, Daniela
De Lentdecker, Chloe
Erdos, Zoltan
Ferreira, Lucien
Greco, Luna
Jarrah, Samira
Kardassi, Dimitra
Leuschner, Renata
Lythgo, Christopher
Medina, Paula
Miron, Ileana
Molnar, Tunde
Nougadere, Alexandre
Pedersen, Ragnor
Reich, Hermine
Sacchi, Angela
Santos, Miguel
Stanek, Alois
Sturma, Juergen
Tarazona, Jose
Theobald, Anne
Vagenende, Benedicte
Verani, Alessia
Villamar‐Bouza, Laura
author_facet Brancato, Alba
Brocca, Daniela
De Lentdecker, Chloe
Erdos, Zoltan
Ferreira, Lucien
Greco, Luna
Jarrah, Samira
Kardassi, Dimitra
Leuschner, Renata
Lythgo, Christopher
Medina, Paula
Miron, Ileana
Molnar, Tunde
Nougadere, Alexandre
Pedersen, Ragnor
Reich, Hermine
Sacchi, Angela
Santos, Miguel
Stanek, Alois
Sturma, Juergen
Tarazona, Jose
Theobald, Anne
Vagenende, Benedicte
Verani, Alessia
Villamar‐Bouza, Laura
collection PubMed
description According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance fenbutatin oxide. Although this active substance is no longer authorised within the EU due to the lack of toxicological data on di‐hydroxy fenbutatin oxide, a compound observed in the metabolism studies but also present as an impurity in the technical active substance, MRLs established by the Codex Alimentarius Commission (CXLs) are still in place. Lacking a full toxicological characterisation of this compound, it was not possible for EFSA to perform an assessment of these CXLs and their incorporation in European legislation cannot be recommended. Nevertheless, available data allowed EFSA to propose a marker residue and a limit of quantification (LOQ) for enforcement against potential illegal uses.
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spelling pubmed-70101342020-07-02 Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005 Brancato, Alba Brocca, Daniela De Lentdecker, Chloe Erdos, Zoltan Ferreira, Lucien Greco, Luna Jarrah, Samira Kardassi, Dimitra Leuschner, Renata Lythgo, Christopher Medina, Paula Miron, Ileana Molnar, Tunde Nougadere, Alexandre Pedersen, Ragnor Reich, Hermine Sacchi, Angela Santos, Miguel Stanek, Alois Sturma, Juergen Tarazona, Jose Theobald, Anne Vagenende, Benedicte Verani, Alessia Villamar‐Bouza, Laura EFSA J Reasoned Opinion According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the maximum residue levels (MRLs) currently established at European level for the pesticide active substance fenbutatin oxide. Although this active substance is no longer authorised within the EU due to the lack of toxicological data on di‐hydroxy fenbutatin oxide, a compound observed in the metabolism studies but also present as an impurity in the technical active substance, MRLs established by the Codex Alimentarius Commission (CXLs) are still in place. Lacking a full toxicological characterisation of this compound, it was not possible for EFSA to perform an assessment of these CXLs and their incorporation in European legislation cannot be recommended. Nevertheless, available data allowed EFSA to propose a marker residue and a limit of quantification (LOQ) for enforcement against potential illegal uses. John Wiley and Sons Inc. 2017-12-12 /pmc/articles/PMC7010134/ /pubmed/32625377 http://dx.doi.org/10.2903/j.efsa.2017.5091 Text en © 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Reasoned Opinion
Brancato, Alba
Brocca, Daniela
De Lentdecker, Chloe
Erdos, Zoltan
Ferreira, Lucien
Greco, Luna
Jarrah, Samira
Kardassi, Dimitra
Leuschner, Renata
Lythgo, Christopher
Medina, Paula
Miron, Ileana
Molnar, Tunde
Nougadere, Alexandre
Pedersen, Ragnor
Reich, Hermine
Sacchi, Angela
Santos, Miguel
Stanek, Alois
Sturma, Juergen
Tarazona, Jose
Theobald, Anne
Vagenende, Benedicte
Verani, Alessia
Villamar‐Bouza, Laura
Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005
title Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005
title_full Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005
title_fullStr Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005
title_full_unstemmed Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005
title_short Review of the existing maximum residue levels for fenbutatin oxide according to Article 12 of Regulation (EC) No 396/2005
title_sort review of the existing maximum residue levels for fenbutatin oxide according to article 12 of regulation (ec) no 396/2005
topic Reasoned Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010134/
https://www.ncbi.nlm.nih.gov/pubmed/32625377
http://dx.doi.org/10.2903/j.efsa.2017.5091
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