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Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses

Influenza A viruses (IAVs) have a remarkable tropism in their ability to circulate in both mammalian and avian species. The IAV NS1 protein is a multifunctional virulence factor that inhibits the type I interferon host response through a myriad of mechanisms. How NS1 has evolved to enable this remar...

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Detalles Bibliográficos
Autores principales:	Muñoz-Moreno, Raquel, Martínez-Romero, Carles, Blanco-Melo, Daniel, Forst, Christian V., Nachbagauer, Raffael, Benitez, Asiel Arturo, Mena, Ignacio, Aslam, Sadaf, Balasubramaniam, Vinod, Lee, Ilseob, Panis, Maryline, Ayllón, Juan, Sachs, David, Park, Man-Seong, Krammer, Florian, tenOever, Benjamin R., García-Sastre, Adolfo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010214/ https://www.ncbi.nlm.nih.gov/pubmed/31851929 http://dx.doi.org/10.1016/j.celrep.2019.11.070

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