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Establishment of a novel human cell line retaining the characteristics of the original pancreatic adenocarcinoma, and evaluation of MEK as a therapeutic target

Pancreatic cancer is a lethal solid malignancy with limited therapeutic options. The development of novel therapeutic drugs requires adequate new cell line models. A new pancreatic cancer cell line, designated PDXPC1, was established from one pancreatic ductal adenocarcinoma (PDAC) patient-derived x...

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Detalles Bibliográficos
Autores principales: Du, Xiaoxiao, He, Kuifeng, Huang, Yingying, Xu, Zhenzhen, Kong, Mei, Zhang, Jing, Cao, Jiang, Teng, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010221/
https://www.ncbi.nlm.nih.gov/pubmed/32124956
http://dx.doi.org/10.3892/ijo.2020.4965

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