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Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population

BACKGROUND: Sterile protection against malaria, most likely mediated by parasite-specific CD8+ T cells, has been achieved by attenuated sporozoite vaccination of animals as well as malaria-naïve and malaria-exposed subjects. The circumsporozoite protein (CSP)-based vaccine, RTS,S, shows low efficacy...

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Detalles Bibliográficos
Autores principales:	Kusi, Kwadwo A., Aggor, Felix E., Amoah, Linda E., Anum, Dorothy, Nartey, Yvonne, Amoako-Sakyi, Daniel, Obiri-Yeboah, Dorcas, Hollingdale, Michael, Ganeshan, Harini, Belmonte, Maria, Peters, Bjoern, Kim, Yohan, Tetteh, John, Kyei-Baafour, Eric, Dodoo, Daniel, Villasante, Eileen, Sedegah, Martha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010280/ https://www.ncbi.nlm.nih.gov/pubmed/32040522 http://dx.doi.org/10.1371/journal.pone.0228177

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