Cargando…

How the initiating ribosome copes with ppGpp to translate mRNAs

During host colonization, bacteria use the alarmones (p)ppGpp to reshape their proteome by acting pleiotropically on DNA, RNA, and protein synthesis. Here, we elucidate how the initiating ribosome senses the cellular pool of guanosine nucleotides and regulates the progression towards protein synthes...

Descripción completa

Detalles Bibliográficos
Autores principales: Vinogradova, Daria S., Zegarra, Victor, Maksimova, Elena, Nakamoto, Jose Alberto, Kasatsky, Pavel, Paleskava, Alena, Konevega, Andrey L., Milón, Pohl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010297/
https://www.ncbi.nlm.nih.gov/pubmed/31995552
http://dx.doi.org/10.1371/journal.pbio.3000593

Ejemplares similares