Cargando…

Risky behaviors and Parkinson disease: A mendelian randomization study

OBJECTIVE: To examine causal associations between risky behavior phenotypes and Parkinson disease using a mendelian randomization approach. METHODS: We used 2-sample mendelian randomization to generate unconfounded estimates using summary statistics from 2 independent, large meta-analyses of genome-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grover, Sandeep, Lill, Christina M., Kasten, Meike, Klein, Christine, Del Greco M, Fabiola, König, Inke R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010323/ https://www.ncbi.nlm.nih.gov/pubmed/31527283 http://dx.doi.org/10.1212/WNL.0000000000008245

Ejemplares similares

A Mendelian randomization study investigating the causal role of inflammation on Parkinson’s disease
por: Bottigliengo, Daniele, et al.
Publicado: (2022)

Evaluating the current state of Mendelian randomization studies: a protocol for a systematic review on methodological and clinical aspects using neurodegenerative disorders as outcome
por: Grover, Sandeep, et al.
Publicado: (2018)

Mendelian randomization: Progressing towards understanding causality
por: König, Inke R., et al.
Publicado: (2018)

Lifestyle factors and clinical severity of Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2023)

Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study
por: Pichler, Irene, et al.
Publicado: (2013)

The Use of Vitamin K2 in Patients With Parkinson's Disease and Mitochondrial Dysfunction (PD-K2): A Theranostic Pilot Study in a Placebo-Controlled Parallel Group Design
por: Prasuhn, Jannik, et al.
Publicado: (2021)

Correction: Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study
por: Pichler, Irene, et al.
Publicado: (2013)

Coffee, smoking and aspirin are associated with age at onset in idiopathic Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2022)

An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial
por: Prasuhn, Jannik, et al.
Publicado: (2019)

Genotype–Phenotype Relations for the Atypical Parkinsonism Genes:MDSGene Systematic Review
por: Wittke, Christina, et al.
Publicado: (2021)

Epidemiology of Parkinson's disease
por: Kasten, Meike, et al.
Publicado: (2007)

Sleep, Pain, and Neurodegeneration: A Mendelian Randomization Study
por: Grover, Sandeep, et al.
Publicado: (2022)

Discordance in monozygotic Parkinson's disease twins – continuum or dichotomy?
por: Balck, Alexander, et al.
Publicado: (2019)

The Parkinson's Disease Mendelian Randomization Research Portal
por: Noyce, Alastair J., et al.
Publicado: (2019)

A framework for the investigation of pleiotropy in two‐sample summary data Mendelian randomization
por: Bowden, Jack, et al.
Publicado: (2017)

The Role of Rare Coding Variants in Parkinson's Disease GWAS Loci
por: Germer, Elisabeth Luisa, et al.
Publicado: (2019)

Validity and Prognostic Value of a Polygenic Risk Score for Parkinson’s Disease
por: Koch, Sebastian, et al.
Publicado: (2021)

Qualitative Characteristics of Depression in Parkinson's Patients and Controls
por: Kritzinger, Cleo, et al.
Publicado: (2015)

The use of two-sample methods for Mendelian randomization analyses on single large datasets
por: Minelli, Cosetta, et al.
Publicado: (2021)

Thyroid function and mood disorders: a Mendelian Randomization study
por: Kuś, Aleksander, et al.
Publicado: (2021)

Relationship between brain iron deposition and mitochondrial dysfunction in idiopathic Parkinson’s disease
por: Prasuhn, Jannik, et al.
Publicado: (2022)

Understanding the effect of smoking and drinking behavior on Parkinson's disease risk: a Mendelian randomization study
por: Domínguez-Baleón, Carmen, et al.
Publicado: (2021)

Parkinson’s disease and Alzheimer’s disease: a Mendelian randomization study
por: Han, Zhifa, et al.
Publicado: (2018)

Vitamin D and the Risk of Depression: A Causal Relationship? Findings from a Mendelian Randomization Study
por: Libuda, Lars, et al.
Publicado: (2019)

Mendelian Randomization — the Key to Understanding Aspects of Parkinson's Disease Causation?
por: Noyce, Alastair J., et al.
Publicado: (2015)

Bidirectional Mendelian randomization study of psychiatric disorders and Parkinson’s disease
por: Wu, Qi, et al.
Publicado: (2023)

Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption
por: Bowden, Jack, et al.
Publicado: (2019)

Altered Resting State Brain Networks in Parkinson’s Disease
por: Göttlich, Martin, et al.
Publicado: (2013)

Religiosity and Preventing Risky Behaviors
por: Mojahed, Azizollah
Publicado: (2014)

Asthma and incident coronary heart disease: an observational and Mendelian randomisation study
por: Valencia-Hernández, Carlos A., et al.
Publicado: (2023)

Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression
por: Bowden, Jack, et al.
Publicado: (2018)

Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression
por: Bowden, Jack, et al.
Publicado: (2018)

Evaluating Lipid‐Lowering Drug Targets for Parkinson's Disease Prevention with Mendelian Randomization
por: Williams, Dylan M., et al.
Publicado: (2020)

Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism
por: Borsche, Max, et al.
Publicado: (2020)

Serum Calcium Levels and Parkinson’s Disease: A Mendelian Randomization Study
por: Wang, Yanchao, et al.
Publicado: (2020)

Ovarian Cancer and Parkinson’s Disease: A Bidirectional Mendelian Randomization Study
por: Guo, Jian-Zeng, et al.
Publicado: (2023)

Tumor Necrosis Factor Inhibition and Parkinson Disease: A Mendelian Randomization Study
por: Kang, Xiaoying, et al.
Publicado: (2021)

Frequent Users of the Emergency Department: Risky Business
por: Grover, Casey A., et al.
Publicado: (2009)

The combined effect of lifestyle factors and polygenic scores on age at onset in Parkinson’s disease
por: Gabbert, Carolin, et al.
Publicado: (2023)

Age at Menarche and Time Spent in Education: A Mendelian Randomization Study
por: Gill, D., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_eqgvasc86lv1ehf0jpf9u7vblj