The thermodynamic profile and molecular interactions of a C(9)-cytisine derivative-binding acetylcholine-binding protein from Aplysia californica

Cytisine, a natural product with high affinity for clinically relevant nicotinic acetylcholine receptors (nAChRs), is used as a smoking-cessation agent. The compound displays an excellent clinical profile and hence there is an interest in derivatives that may be further improved or find use in the t...

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Detalles Bibliográficos
Autores principales: Davis, Samuel, Rego Campello, Hugo, Gallagher, Timothy, Hunter, William N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010356/
https://www.ncbi.nlm.nih.gov/pubmed/32039888
http://dx.doi.org/10.1107/S2053230X20001168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010356/
https://www.ncbi.nlm.nih.gov/pubmed/32039888
http://dx.doi.org/10.1107/S2053230X20001168

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