Cargando…

Screening the Drug:H(+) Antiporter Family for a Role in Biofilm Formation in Candida glabrata

Biofilm formation and drug resistance are two key pathogenesis traits exhibited by Candida glabrata as a human pathogen. Interestingly, specific pathways appear to be in the crossroad between the two phenomena, making them promising targets for drug development. In this study, the 10 multidrug resis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santos, Rui, Cavalheiro, Mafalda, Costa, Catarina, Takahashi-Nakaguchi, Azusa, Okamoto, Michiyo, Chibana, Hiroji, Teixeira, Miguel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010593/ https://www.ncbi.nlm.nih.gov/pubmed/32117803 http://dx.doi.org/10.3389/fcimb.2020.00029

Ejemplares similares

The dual role of candida glabrata drug:H+ antiporter CgAqr1 (ORF CAGL0J09944g) in antifungal drug and acetic acid resistance
por: Costa, Catarina, et al.
Publicado: (2013)

A New Determinant of Candida glabrata Virulence: The Acetate Exporter CgDtr1
por: Romão, Daniela, et al.
Publicado: (2017)

Evaluation of Antifungal Selective Toxicity Using Candida glabrata ERG25 and Human SC4MOL Knock-In Strains
por: Nakano, Keiko, et al.
Publicado: (2023)

Clotrimazole Drug Resistance in Candida glabrata Clinical Isolates Correlates with Increased Expression of the Drug:H(+) Antiporters CgAqr1, CgTpo1_1, CgTpo3, and CgQdr2
por: Costa, Catarina, et al.
Publicado: (2016)

From the first touch to biofilm establishment by the human pathogen Candida glabrata: a genome-wide to nanoscale view
por: Cavalheiro, Mafalda, et al.
Publicado: (2021)

Role of CgTpo4 in Polyamine and Antimicrobial Peptide Resistance: Determining Virulence in Candida glabrata
por: Cavalheiro, Mafalda, et al.
Publicado: (2021)

In Candida glabrata, ERMES Component GEM1 Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility
por: Okamoto, Michiyo, et al.
Publicado: (2023)

Candida glabrata Transcription Factor Rpn4 Mediates Fluconazole Resistance through Regulation of Ergosterol Biosynthesis and Plasma Membrane Permeability
por: Pais, Pedro, et al.
Publicado: (2020)

Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants
por: Pais, Pedro, et al.
Publicado: (2022)

KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata
por: Tanaka, Yutaka, et al.
Publicado: (2016)

A Transcriptomics Approach To Unveiling the Mechanisms of In Vitro Evolution towards Fluconazole Resistance of a Candida glabrata Clinical Isolate
por: Cavalheiro, Mafalda, et al.
Publicado: (2018)

Membrane Proteomics Analysis of the Candida glabrata Response to 5-Flucytosine: Unveiling the Role and Regulation of the Drug Efflux Transporters CgFlr1 and CgFlr2
por: Pais, Pedro, et al.
Publicado: (2016)

Insight Into the Properties and Immunoregulatory Effect of Extracellular Vesicles Produced by Candida glabrata, Candida parapsilosis, and Candida tropicalis Biofilms
por: Kulig, Kamila, et al.
Publicado: (2022)

The Lack of SNARE Protein Homolog Syn8 Influences Biofilm Formation of Candida glabrata
por: Chen, Xinyue, et al.
Publicado: (2021)

New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae
por: Costa, Catarina, et al.
Publicado: (2015)

Erg25 Controls Host-Cholesterol Uptake Mediated by Aus1p-Associated Sterol-Rich Membrane Domains in Candida glabrata
por: Okamoto, Michiyo, et al.
Publicado: (2022)

The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata
por: Bernardo, Ruben T., et al.
Publicado: (2016)

Characterization of the Candida glabrata Transcription Factor CgMar1: Role in Azole Susceptibility
por: Pais, Pedro, et al.
Publicado: (2022)

Characterization of Awp14, A Novel Cluster III Adhesin Identified in a High Biofilm-Forming Candida glabrata Isolate
por: Fernández-Pereira, Jordan, et al.
Publicado: (2021)

A new regulator in the crossroads of oxidative stress resistance and virulence in Candida glabrata: The transcription factor CgTog1
por: Pais, Pedro, et al.
Publicado: (2020)

The drug:H(+) antiporters of family 2 (DHA2), siderophore transporters (ARN) and glutathione:H(+) antiporters (GEX) have a common evolutionary origin in hemiascomycete yeasts
por: Dias, Paulo Jorge, et al.
Publicado: (2013)

Microevolution of the pathogenic yeasts Candida albicans and Candida glabrata during antifungal therapy and host infection
por: Pais, Pedro, et al.
Publicado: (2019)

Ibrexafungerp, a Novel Oral Triterpenoid Antifungal in Development: Overview of Antifungal Activity Against Candida glabrata
por: Gamal, Ahmed, et al.
Publicado: (2021)

Yap5 Competes With Hap4 for the Regulation of Iron Homeostasis Genes in the Human Pathogen Candida glabrata
por: Delaveau, Thierry, et al.
Publicado: (2021)

Presence of Candida tropicalis on Staphylococcus epidermidis Biofilms Facilitated Biofilm Production and Candida Dissemination: An Impact of Fungi on Bacterial Biofilms
por: Phuengmaung, Pornpimol, et al.
Publicado: (2021)

Colonized patients by Candida auris: Third and largest outbreak in Brazil and impact of biofilm formation
por: de Melo, Camylla Carvalho, et al.
Publicado: (2023)

Candida Biofilms: Threats, Challenges, and Promising Strategies
por: Cavalheiro, Mafalda, et al.
Publicado: (2018)

Evaluation of the biofilm life cycle between Candida albicans and Candida tropicalis
por: Atiencia-Carrera, María Belén, et al.
Publicado: (2022)

Inhibitory effects of vaginal Lactobacilli on Candida albicans growth, hyphal formation, biofilm development, and epithelial cell adhesion
por: Takano, Tomonori, et al.
Publicado: (2023)

Screening the CALIBR ReFRAME Library in Search for Inhibitors of Candida auris Biofilm Formation
por: Wall, Gina, et al.
Publicado: (2020)

The Role of Candida albicans Virulence Factors in the Formation of Multispecies Biofilms With Bacterial Periodontal Pathogens
por: Satala, Dorota, et al.
Publicado: (2022)

SAGA Complex Subunits in Candida albicans Differentially Regulate Filamentation, Invasiveness, and Biofilm Formation
por: Rashid, Saima, et al.
Publicado: (2022)

Lichen Polyphenolic Compounds for the Eradication of Candida albicans Biofilms
por: Girardot, Marion, et al.
Publicado: (2021)

Photodynamic Therapy Is Effective Against Candida auris Biofilms
por: Bapat, Priyanka S., et al.
Publicado: (2021)

Promising Anti-Biofilm Agents and Phagocytes Enhancers for the Treatment of Candida albicans Biofilm–Associated Infections
por: Tartor, Yasmine H., et al.
Publicado: (2022)

Establishment of a rapid diagnosis method for Candida glabrata based on the ITS2 gene using recombinase polymerase amplification combined with lateral flow strips
por: Wang, Kun, et al.
Publicado: (2022)

Recent Advances and Opportunities in the Study of Candida albicans Polymicrobial Biofilms
por: Pohl, Carolina H.
Publicado: (2022)

Eosinophilic cystitis caused by Candida glabrata: A case report
por: Duong, David T., et al.
Publicado: (2019)

A rare case of emphysematous cystitis due to Candida glabrata
por: Sapkalova, Viktoriya, et al.
Publicado: (2023)

Synergistic Interaction of Piperine and Thymol on Attenuation of the Biofilm Formation, Hyphal Morphogenesis and Phenotypic Switching in Candida albicans
por: Priya, Arumugam, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_o00v6e7273sfr669t9v5ghjeg9