The common message of constraint-based optimization approaches: overflow metabolism is caused by two growth-limiting constraints

Living cells can express different metabolic pathways that support growth. The criteria that determine which pathways are selected in which environment remain unclear. One recurrent selection is overflow metabolism: the simultaneous usage of an ATP-efficient and -inefficient pathway, shown for examp...

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Detalles Bibliográficos
Autores principales: de Groot, Daan H., Lischke, Julia, Muolo, Riccardo, Planqué, Robert, Bruggeman, Frank J., Teusink, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010627/
https://www.ncbi.nlm.nih.gov/pubmed/31758233
http://dx.doi.org/10.1007/s00018-019-03380-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010627/
https://www.ncbi.nlm.nih.gov/pubmed/31758233
http://dx.doi.org/10.1007/s00018-019-03380-2

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