Differences in Transcriptional Dynamics Between T-cells and Macrophages as Determined by a Three-State Mathematical Model

HIV-1 viral transcription persists in patients despite antiretroviral treatment, potentially due to intermittent HIV-1 LTR activation. While several mathematical models have been explored in the context of LTR-protein interactions, in this work for the first time HIV-1 LTR model featuring repressed,...

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Detalles Bibliográficos
Autores principales: DeMarino, Catherine, Cowen, Maria, Pleet, Michelle L., Pinto, Daniel O., Khatkar, Pooja, Erickson, James, Docken, Steffen S., Russell, Nicholas, Reichmuth, Blake, Phan, Tin, Kuang, Yang, Anderson, Daniel M., Emelianenko, Maria, Kashanchi, Fatah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010665/
https://www.ncbi.nlm.nih.gov/pubmed/32042107
http://dx.doi.org/10.1038/s41598-020-59008-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010665/
https://www.ncbi.nlm.nih.gov/pubmed/32042107
http://dx.doi.org/10.1038/s41598-020-59008-0

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