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Regulation of bone metabolism by megakaryocytes in a paracrine manner
Megakaryocytes (MKs) play key roles in regulating bone metabolism. To test the roles of MK-secreted factors, we investigated whether MK and promegakaryocyte (pro-MK) conditioned media (CM) may affect bone formation and resorption. K562 cell lines were differentiated into mature MKs. Mouse bone marro...
Autores principales: | Lee, Young-Sun, Kwak, Mi Kyung, Moon, Sung-Ah, Choi, Young Jin, Baek, Ji Eun, Park, Suk Young, Kim, Beom-Jun, Lee, Seung Hun, Koh, Jung-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010738/ https://www.ncbi.nlm.nih.gov/pubmed/32042021 http://dx.doi.org/10.1038/s41598-020-59250-6 |
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