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Regulation of bone metabolism by megakaryocytes in a paracrine manner

Megakaryocytes (MKs) play key roles in regulating bone metabolism. To test the roles of MK-secreted factors, we investigated whether MK and promegakaryocyte (pro-MK) conditioned media (CM) may affect bone formation and resorption. K562 cell lines were differentiated into mature MKs. Mouse bone marro...

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Detalles Bibliográficos
Autores principales: Lee, Young-Sun, Kwak, Mi Kyung, Moon, Sung-Ah, Choi, Young Jin, Baek, Ji Eun, Park, Suk Young, Kim, Beom-Jun, Lee, Seung Hun, Koh, Jung-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010738/
https://www.ncbi.nlm.nih.gov/pubmed/32042021
http://dx.doi.org/10.1038/s41598-020-59250-6

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