Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK

The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity. NatE co-translationally acetylates the N-terminus of half the proteome to mediate diverse biological processe...

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Detalles Bibliográficos
Autores principales: Deng, Sunbin, McTiernan, Nina, Wei, Xuepeng, Arnesen, Thomas, Marmorstein, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010799/
https://www.ncbi.nlm.nih.gov/pubmed/32042062
http://dx.doi.org/10.1038/s41467-020-14584-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010799/
https://www.ncbi.nlm.nih.gov/pubmed/32042062
http://dx.doi.org/10.1038/s41467-020-14584-7

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