Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase

Autophagy is essential for cellular survival and energy homeostasis under nutrient deprivation. Despite the emerging importance of nuclear events in autophagy regulation, epigenetic control of autophagy gene transcription remains unclear. Here, we report fasting-induced Fibroblast Growth Factor-21 (...

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Detalles Bibliográficos
Autores principales: Byun, Sangwon, Seok, Sunmi, Kim, Young-Chae, Zhang, Yang, Yau, Peter, Iwamori, Naoki, Xu, H. Eric, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010817/
https://www.ncbi.nlm.nih.gov/pubmed/32042044
http://dx.doi.org/10.1038/s41467-020-14384-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010817/
https://www.ncbi.nlm.nih.gov/pubmed/32042044
http://dx.doi.org/10.1038/s41467-020-14384-z

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