Monomeric C-Reactive Protein in Serum With Markedly Elevated CRP Levels Shares Common Calcium-Dependent Ligand Binding Properties With an in vitro Dissociated Form of C-Reactive Protein

A monomeric form of C-reactive protein (CRP) which precipitates with cell wall pneumococcal C polysaccharide (CWPS) and retains the ability to reversibly bind to its ligand phosphocholine has been produced through urea-induced dissociation at an optimized concentration of 3 M urea over a 10 weeks pe...

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Detalles Bibliográficos
Autores principales: Williams, Robert D., Moran, Jennifer A., Fryer, Anthony A., Littlejohn, Jamie R., Williams, Harry M., Greenhough, Trevor J., Shrive, Annette K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010908/
https://www.ncbi.nlm.nih.gov/pubmed/32117266
http://dx.doi.org/10.3389/fimmu.2020.00115

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