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CAR T Cells Redirected to CD44v6 Control Tumor Growth in Lung and Ovary Adenocarcinoma Bearing Mice

The main challenge of adoptive therapy with Chimeric Antigen Receptor modified T cells (CAR T) is the application to the field of solid tumors, where the identification of a proper antigen has emerged as one of the major drawbacks to CAR T cell treatment success. CD44 is a glycoprotein involved in c...

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Detalles Bibliográficos
Autores principales:	Porcellini, Simona, Asperti, Claudia, Corna, Stefano, Cicoria, Eleonora, Valtolina, Veronica, Stornaiuolo, Anna, Valentinis, Barbara, Bordignon, Claudio, Traversari, Catia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010926/ https://www.ncbi.nlm.nih.gov/pubmed/32117253 http://dx.doi.org/10.3389/fimmu.2020.00099

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