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PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

OBJECTIVE: The liver is regularly exposed to changing metabolic and inflammatory environments. It must sense and adapt to metabolic need while balancing resources required to protect itself from insult. Peroxisome proliferator activated receptor gamma coactivator-1 alpha (PGC-1α) is a transcriptiona...

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Detalles Bibliográficos
Autores principales: Léveillé, Mélissa, Besse-Patin, Aurèle, Jouvet, Nathalie, Gunes, Aysim, Sczelecki, Sarah, Jeromson, Stewart, Khan, Naveen P., Baldwin, Cindy, Dumouchel, Annie, Correia, Jorge C., Jannig, Paulo R., Boulais, Jonathan, Ruas, Jorge L., Estall, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011010/
https://www.ncbi.nlm.nih.gov/pubmed/32180561
http://dx.doi.org/10.1016/j.molmet.2020.01.004