Reproducibility, reliability and variability of FA and MD in the older healthy population: A test-retest multiparametric analysis

• In older healthy subjects, FA and MD show overall good test-retest reliability & reproducibility. • MD is sistematically more reproducible than FA across the entire brain anatomy. • FA is more reliable than MD in subcortical white matter regions. • In high reliability & low reproducibility...

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Detalles Bibliográficos
Autores principales: Luque Laguna, Pedro A., Combes, Anna J.E., Streffer, Johannes, Einstein, Steven, Timmers, Maarten, Williams, Steve C.R., Dell'Acqua, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011084/
https://www.ncbi.nlm.nih.gov/pubmed/32035272
http://dx.doi.org/10.1016/j.nicl.2020.102168
Descripción
Sumario:• In older healthy subjects, FA and MD show overall good test-retest reliability & reproducibility. • MD is sistematically more reproducible than FA across the entire brain anatomy. • FA is more reliable than MD in subcortical white matter regions. • In high reliability & low reproducibility regions, variability between subjects is high and statistical power is low. • In low reliability & high reproducibility regions, variability between subjects is low and statistical power is high.

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