MicroRNA‐129‐1‐3p protects cardiomyocytes from pirarubicin‐induced apoptosis by down‐regulating the GRIN2D‐mediated Ca(2+) signalling pathway

Pirarubicin (THP), an anthracycline anticancer drug, is a first‐line therapy for various solid tumours and haematologic malignancies. However, THP can cause dose‐dependent cumulative cardiac damage, which limits its therapeutic window. The mechanisms underlying THP cardiotoxicity are not fully under...

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Detalles Bibliográficos
Autores principales: Li, Qi, Qin, Meng, Tan, Qi, Li, Tengteng, Gu, Zehui, Huang, Peng, Ren, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011137/
https://www.ncbi.nlm.nih.gov/pubmed/31957170
http://dx.doi.org/10.1111/jcmm.14908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011137/
https://www.ncbi.nlm.nih.gov/pubmed/31957170
http://dx.doi.org/10.1111/jcmm.14908

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