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Pioglitazone attenuates advanced glycation end products‐induced apoptosis and calcification by modulating autophagy in tendon‐derived stem cells

Diabetes mellitus (DM) is one of the prominent risk factors for pathological development and progression of tendinopathy. One feature of DM‐related changes in tendinopathy is accumulation of advanced glycation end products (AGEs) in affected tendons. Pioglitazone (Pio), a peroxisome proliferator‐act...

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Detalles Bibliográficos
Autores principales: Xu, Langhai, Xu, Kai, Wu, Zhipeng, Chen, Zhonggai, He, Yuzhe, Ma, Chiyuan, Moqbel, Safwat A. A., Ran, Jisheng, Zhang, Caihua, Wu, Lidong, Xiong, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011144/
https://www.ncbi.nlm.nih.gov/pubmed/31957239
http://dx.doi.org/10.1111/jcmm.14901