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Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy‐induced bone loss
Osteoclasts are multinucleated cells derived from the monocyte/macrophage cell lineage under the regulation of receptor activator of nuclear factor‐κB ligand (RANKL). In previous studies, stimulation by RANKL during osteoclastogenesis was shown to induce a metabolic switch to enhanced glycolytic met...
Autores principales: | Wang, Jia, Guan, Hanfeng, Liu, Hui, Lei, Zuowei, Kang, Honglei, Guo, Qian, Dong, Yimin, Liu, Huiyong, Sun, Yunlong, Fang, Zhong, Li, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011148/ https://www.ncbi.nlm.nih.gov/pubmed/31880389 http://dx.doi.org/10.1111/jcmm.14912 |
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