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Angiotensin II‐induced redox‐sensitive SGLT1 and 2 expression promotes high glucose‐induced endothelial cell senescence

High glucose (HG)‐induced endothelial senescence and dysfunction contribute to the increased cardiovascular risk in diabetes. Empagliflozin, a selective sodium glucose co‐transporter2 (SGLT2) inhibitor, reduced the risk of cardiovascular mortality in type 2 diabetic patients but the protective mecha...

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Detalles Bibliográficos
Autores principales: Khemais‐Benkhiat, Sonia, Belcastro, Eugenia, Idris‐Khodja, Noureddine, Park, Sin‐Hee, Amoura, Lamia, Abbas, Malak, Auger, Cyril, Kessler, Laurence, Mayoux, Eric, Toti, Florence, Schini‐Kerth, Valérie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011151/
https://www.ncbi.nlm.nih.gov/pubmed/30929316
http://dx.doi.org/10.1111/jcmm.14233

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