A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells

BACKGROUND: Quiescence (G0) is a transient, cell cycle-arrested state. By entering G0, cancer cells survive unfavorable conditions such as chemotherapy and cause relapse. While G0 cells have been studied at the transcriptome level, how post-transcriptional regulation contributes to their chemoresist...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Sooncheol, Micalizzi, Douglas, Truesdell, Samuel S., Bukhari, Syed I. A., Boukhali, Myriam, Lombardi-Story, Jennifer, Kato, Yasutaka, Choo, Min-Kyung, Dey-Guha, Ipsita, Ji, Fei, Nicholson, Benjamin T., Myers, David T., Lee, Dongjun, Mazzola, Maria A., Raheja, Radhika, Langenbucher, Adam, Haradhvala, Nicholas J., Lawrence, Michael S., Gandhi, Roopali, Tiedje, Christopher, Diaz-Muñoz, Manuel D., Sweetser, David A., Sadreyev, Ruslan, Sykes, David, Haas, Wilhelm, Haber, Daniel A., Maheswaran, Shyamala, Vasudevan, Shobha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011231/
https://www.ncbi.nlm.nih.gov/pubmed/32039742
http://dx.doi.org/10.1186/s13059-020-1936-4

Ejemplares similares

Ejemplares similares