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A randomised, double-blind, active placebo-controlled, parallel groups, dose-response study of scopolamine hydrobromide (4–6 μg/kg) in patients with major depressive disorder
BACKGROUND: Depressive disorders are a leading cause of disability, but current behavioural and pharmacological therapies have a slow onset of response, typically taking several weeks before achieving efficacy. Prior studies using triplicate intravenous scopolamine infusions have been shown to reduc...
Autores principales: | Chen, Joseph C. C., Sumner, Rachael L., Krishnamurthy Naga, Venkat, Hoeh, Nicholas, Ayeni, Hafis Adetokunbo, Singh, Vikrant, Sundram, Frederick, Campbell, Douglas, Muthukumaraswamy, Suresh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011244/ https://www.ncbi.nlm.nih.gov/pubmed/32041658 http://dx.doi.org/10.1186/s13063-020-4089-6 |
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