Involvement of CXCL12/CXCR4 in the motility of human first-trimester endometrial epithelial cells through an autocrine mechanism by activating PI3K/AKT signaling

BACKGROUND: CXCL12(chemokine ligand 12, CXCL12) and its receptors CXCR4 are widely expressed in maternal-fetal interface and plays an adjust role in materno-fetal dialogue and immune tolerance during early pregnancy. This study aimed to evaluate the role and mechanism of self-derived CXCL12 in modul...

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Detalles Bibliográficos
Autores principales: Zheng, Jiayi, Qu, Danni, Wang, Chen, Ding, Ling, Zhou, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011269/
https://www.ncbi.nlm.nih.gov/pubmed/32041571
http://dx.doi.org/10.1186/s12884-020-2788-3

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