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DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma
BACKGROUND: Accumulating evidence shows that long noncoding RNAs (lncRNAs) are important regulator molecules involved in diverse biological processes. Acquired drug resistance is a major challenge in the clinical treatment of glioblastoma (GBM), and lncRNAs have been shown to play a role in chemothe...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011291/ https://www.ncbi.nlm.nih.gov/pubmed/32039732 http://dx.doi.org/10.1186/s12943-020-1137-5 |