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Caplacizumab in adult patients with acquired thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura (TTP) is usually a fatal disease caused by a deficiency of the metalloproteinase, ADAMTS13, often due to autoimmunity. This leads to the development of pathogenic multimers of von Willebrand factor (vWF), causing an inappropriate interaction of platelets and vWF....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011322/ https://www.ncbi.nlm.nih.gov/pubmed/32095224 http://dx.doi.org/10.1177/2040620720902904 |