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Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers

RATIONALE: Vascular permeability is a hallmark of acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury pathobiology; however, the mechanisms underlying this vascular dysregulation remain unclear, thereby impairing the development of desperately needed effective therapeutics....

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Detalles Bibliográficos
Autores principales: Camp, Sara M., Marciniak, Alexander, Chiang, Eddie T., Garcia, Alexander N., Bittman, Robert, Polt, Robin, Perez, Ruth G., Dudek, Steven M., Garcia, Joe G. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011338/
https://www.ncbi.nlm.nih.gov/pubmed/32095229
http://dx.doi.org/10.1177/2045894020905521

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