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Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers
RATIONALE: Vascular permeability is a hallmark of acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury pathobiology; however, the mechanisms underlying this vascular dysregulation remain unclear, thereby impairing the development of desperately needed effective therapeutics....
Autores principales: | Camp, Sara M., Marciniak, Alexander, Chiang, Eddie T., Garcia, Alexander N., Bittman, Robert, Polt, Robin, Perez, Ruth G., Dudek, Steven M., Garcia, Joe G. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011338/ https://www.ncbi.nlm.nih.gov/pubmed/32095229 http://dx.doi.org/10.1177/2045894020905521 |
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