Zoledronic acid inhibits TSC2-null cell tumor growth via RhoA/YAP signaling pathway in mouse models of lymphangioleiomyomatosis

BACKGROUND: This study is to investigate the effects of zoledronic acid (ZA) on TSC2-null cell proliferation and on the tumor progression and recurrence in mouse models of lymphangioleiomyomatosis (LAM). METHODS: Subcutaneous mouse models and LAM mouse models were established. Immunohistochemistry a...

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Detalles Bibliográficos
Autores principales: Zhao, Dandan, Wu, Jing, Zhao, Yinjuan, Shao, Wei, Cheng, Qi, Shao, Xiaoyan, Yuan, Xianwen, Ye, Juan, Gao, Jianpu, Jin, Meiling, Li, Chaojun, Chen, Xiaolin, Zhao, Yue, Xue, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011352/
https://www.ncbi.nlm.nih.gov/pubmed/32063747
http://dx.doi.org/10.1186/s12935-020-1131-4

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