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Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study

BACKGROUND: There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. METHODS: We conducted a cross-s...

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Autores principales: Mubangizi, Vincent, Maling, Samuel, Obua, Celestino, Tsai, Alexander C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011370/
https://www.ncbi.nlm.nih.gov/pubmed/32041525
http://dx.doi.org/10.1186/s12877-020-1461-z
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author Mubangizi, Vincent
Maling, Samuel
Obua, Celestino
Tsai, Alexander C.
author_facet Mubangizi, Vincent
Maling, Samuel
Obua, Celestino
Tsai, Alexander C.
author_sort Mubangizi, Vincent
collection PubMed
description BACKGROUND: There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. METHODS: We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia. RESULTS: Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10–1.03, p<0.001), having some formal education (AOR, 0.57; 95% CI, 0.41–0.81, p = 0.001), exercise (AOR, 0.44; 95% CI, 0.27–0.72, p = 0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24–0.77, p = 0.001). CONCLUSIONS: In this population-based sample of older-age adults in rural Uganda, nearly one-fifth screened positive for dementia.
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spelling pubmed-70113702020-02-14 Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study Mubangizi, Vincent Maling, Samuel Obua, Celestino Tsai, Alexander C. BMC Geriatr Research Article BACKGROUND: There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. METHODS: We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia. RESULTS: Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10–1.03, p<0.001), having some formal education (AOR, 0.57; 95% CI, 0.41–0.81, p = 0.001), exercise (AOR, 0.44; 95% CI, 0.27–0.72, p = 0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24–0.77, p = 0.001). CONCLUSIONS: In this population-based sample of older-age adults in rural Uganda, nearly one-fifth screened positive for dementia. BioMed Central 2020-02-10 /pmc/articles/PMC7011370/ /pubmed/32041525 http://dx.doi.org/10.1186/s12877-020-1461-z Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Mubangizi, Vincent
Maling, Samuel
Obua, Celestino
Tsai, Alexander C.
Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study
title Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study
title_full Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study
title_fullStr Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study
title_full_unstemmed Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study
title_short Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study
title_sort prevalence and correlates of alzheimer’s disease and related dementias in rural uganda: cross-sectional, population-based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011370/
https://www.ncbi.nlm.nih.gov/pubmed/32041525
http://dx.doi.org/10.1186/s12877-020-1461-z
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