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Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study
BACKGROUND: There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. METHODS: We conducted a cross-s...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011370/ https://www.ncbi.nlm.nih.gov/pubmed/32041525 http://dx.doi.org/10.1186/s12877-020-1461-z |
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author | Mubangizi, Vincent Maling, Samuel Obua, Celestino Tsai, Alexander C. |
author_facet | Mubangizi, Vincent Maling, Samuel Obua, Celestino Tsai, Alexander C. |
author_sort | Mubangizi, Vincent |
collection | PubMed |
description | BACKGROUND: There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. METHODS: We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia. RESULTS: Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10–1.03, p<0.001), having some formal education (AOR, 0.57; 95% CI, 0.41–0.81, p = 0.001), exercise (AOR, 0.44; 95% CI, 0.27–0.72, p = 0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24–0.77, p = 0.001). CONCLUSIONS: In this population-based sample of older-age adults in rural Uganda, nearly one-fifth screened positive for dementia. |
format | Online Article Text |
id | pubmed-7011370 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-70113702020-02-14 Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study Mubangizi, Vincent Maling, Samuel Obua, Celestino Tsai, Alexander C. BMC Geriatr Research Article BACKGROUND: There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. METHODS: We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia. RESULTS: Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10–1.03, p<0.001), having some formal education (AOR, 0.57; 95% CI, 0.41–0.81, p = 0.001), exercise (AOR, 0.44; 95% CI, 0.27–0.72, p = 0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24–0.77, p = 0.001). CONCLUSIONS: In this population-based sample of older-age adults in rural Uganda, nearly one-fifth screened positive for dementia. BioMed Central 2020-02-10 /pmc/articles/PMC7011370/ /pubmed/32041525 http://dx.doi.org/10.1186/s12877-020-1461-z Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Mubangizi, Vincent Maling, Samuel Obua, Celestino Tsai, Alexander C. Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study |
title | Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study |
title_full | Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study |
title_fullStr | Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study |
title_full_unstemmed | Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study |
title_short | Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study |
title_sort | prevalence and correlates of alzheimer’s disease and related dementias in rural uganda: cross-sectional, population-based study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011370/ https://www.ncbi.nlm.nih.gov/pubmed/32041525 http://dx.doi.org/10.1186/s12877-020-1461-z |
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