Comparing methotrexate monotherapy with methotrexate plus leflunomide combination therapy in psoriatic arthritis: protocol of a randomized, placebo-controlled, double-blind clinical trial (COMPLETE-PsA)

BACKGROUND: Both methotrexate (MTX) and leflunomide (LEF) are registered and regularly prescribed as first-line treatments for the use in patients with psoriatic arthritis (PsA) and they are occasionally used in combination. However, evidence about their individual, and especially combined efficacy,...

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Detalles Bibliográficos
Autores principales: Mulder, Michelle L. M., Vriezekolk, Johanna E., den Broeder, Nathan, Mahler, Elien A. M., Helliwell, Philip S., van den Hoogen, Frank H. J., den Broeder, Alfons A., Wenink, Mark H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011519/
https://www.ncbi.nlm.nih.gov/pubmed/32041657
http://dx.doi.org/10.1186/s13063-020-4097-6

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