Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor

Pyridinium containing sulfonamides have been largely investigated as carbonic anhydrase inhibitors (CAIs), showing interesting selectivity features. Nevertheless, only few structural studies are so far available on adducts that these compounds form with diverse CA isoforms. In this paper, we report...

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Detalles Bibliográficos
Autores principales: Alterio, Vincenzo, Esposito, Davide, Monti, Simona Maria, Supuran, Claudiu T., De Simone, Giuseppina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011996/
https://www.ncbi.nlm.nih.gov/pubmed/29199489
http://dx.doi.org/10.1080/14756366.2017.1405263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011996/
https://www.ncbi.nlm.nih.gov/pubmed/29199489
http://dx.doi.org/10.1080/14756366.2017.1405263

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