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Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study

A new series of 4,6-disubstituted 2-(4-(dimethylamino)styryl)quinoline 4a,b–9a,b was synthesized by the reaction of 2-(4-(dimethylamino)styryl)-6-substituted quinoline-4-carboxylic acids 3a,b with thiosemicarbazide, p-hydroxybenzaldehyde, ethylcyanoacetate, and 2,4-pentandione. In addition, the anti...

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Detalles Bibliográficos
Autores principales:	El-Sayed, Magda A.-A., El-Husseiny, Walaa M., Abdel-Aziz, Naglaa I., El-Azab, Adel S., Abuelizz, Hatem A., Abdel-Aziz, Alaa A.-M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012010/ https://www.ncbi.nlm.nih.gov/pubmed/29251017 http://dx.doi.org/10.1080/14756366.2017.1407926

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