Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

Introduction: Transporters comprising the blood-brain barrier complicate delivery of many therapeutics to the central nervous system. The present study ascertained whether the natural product botryllamide G is viable for in vivo inhibition of ABCG2 using lapatinib as a probe for ABCB1 and ABCG2-medi...

Descripción completa

Detalles Bibliográficos
Autores principales: Strope, Jonathan D., Peer, Cody J., Sissung, Tristan M., Hall, O. Morgan, Huang, Phoebe A., Harris, Emily M., Gustafson, Kirk R., Henrich, Curtis J., Sigano, Dina M., Pauly, Gary T., Schneider, Joel P., Bates, Susan E., Figg, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012088/
https://www.ncbi.nlm.nih.gov/pubmed/31709896
http://dx.doi.org/10.1080/15384047.2019.1683324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012088/
https://www.ncbi.nlm.nih.gov/pubmed/31709896
http://dx.doi.org/10.1080/15384047.2019.1683324

Ejemplares similares