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Clinically Actionable Insights into Initial and Matched Recurrent Glioblastomas to Inform Novel Treatment Approaches
Glioblastoma is the most common primary adult brain tumour, and despite optimal treatment, the median survival is 12–15 months. Patients with matched recurrent glioblastomas were investigated to try to find actionable mutations. Tumours were profiled using a validated DNA-based gene panel. Copy numb...
Autores principales: | Ellis, H. P., McInerney, C. E., Schrimpf, D., Sahm, F., Stupnikov, A., Wadsley, M., Wragg, C., White, P., Prise, K. M., McArt, D. G., Kurian, K. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7012245/ https://www.ncbi.nlm.nih.gov/pubmed/32082376 http://dx.doi.org/10.1155/2019/4878547 |
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